[Synthesis and binding affinity to human steroid hormone receptors of 3-phenoxy-4-hydroxycoumarins and 3-phenoxy-4-phenylcoumarins]. / Synthèse et affinité de fixation aux récepteurs d'hormones stéroïdes humains de 3-phénoxy-4-hydroxycoumarines et de 3-phénoxy-4-phénylcoumarines.

The synthesis and the study of the binding affinity to human receptors of glucocorticoids, mineralcorticoids, androgens, estrogens and progesterone of 3-phenoxy-4-hydroxycoumarins and 3-phenoxy-4-phenylcoumarins were performed. It shows the absence of any binding affinity of all these derivatives to glucocorticoid and mineralcorticoid receptors and a non-selective binding affinity to androgen, oestrogen and progesterone receptors with 3-phenoxy-4-phényl-coumarins.

[Free radical scavenging activity of 4-hydroxycoumarin derivatives]. / Activité antiradicalaire de dérivés substitués de la 4-hydroxycoumarine.

The study of the relationships between the structure and the free radical scavenging activity of substituted 4-hydroxycoumarine derivatives, indicates the favorable effect of electron donating substituents.