1.
Molecules
; 16(1): 92-9, 2010 Dec 28.
Article
in English
| MEDLINE
| ID: mdl-21189457
ABSTRACT
An efficient and improved procedure for the synthesis of 1,4-diazepine and 1,5-benzodiazepine derivatives via the reaction of ketimine intermediates with aldehydes in the presence of Keggin-type heteropolyacids (HPAs) was developed. High yields and short reaction times were obtained for both electron-releasing and electron-withdrawing substituted 1,4-diazepine and 1,5-benzodiazepines derivatives.