[The advanced training of the therapists in a local medical association without interrupting their performance of service obligations as a variant in the postgraduate raising of qualifications on a permanent basis]. / Usovershenstvovanie terapevtov v territorial'nom meditsinskom ob''edinenii bez otryva ot vypolneniia sluzhebnykh obiazannostei kak variant poslediplomnogo povysheniia kvalifikatsii na postoiannoi osnove.

A new approach to continuous medical education of district physicians implies 4-5 annual (100-120 teaching periods) which are delivered to groups of 10 medical professionals for 4 days a week. The education is intended annually for 50 district therapists and other specialists and is especially helpful if outpatient service is organized according to the team principle (obstetrician, pediatrician, therapist). The lectures cover present-day advances in medical practice and research with special emphasis to borderline conditions.

[Adenohypophyseal hormone and corticosteroid content in the blood and urine in light mechanical injury]. / Soderzhanie nekotorykh gormonov adenogipofiza i kortikosteroidov v krovi i mochi bol'nykh pri legkoi mekhanicheskoi travme.

A considerably increased content of adrenocorticotropic, somatotropic and thyreo-stimulating hormones of the hypophysis in the blood serum, as well as corticosteroids in the blood and especially in the day urine was noted in 27 male patients with the first 4--8 days after light mechanical traumas not resulting in pronounced disturbances of homeostasis and having favourable outcomes. It has been shown that a simultaneous assessment of cortisole and corticosterone in the day urine is most informative among the studied forms of adrenal hormones (17-OCS, cortisole, corticosterone) in the evaluation of the functional state of the adrenal cortex and corticosteroid balance in the organism of the patients.

[Shifts in the electrolyte and energy metabolism of rat myocardium in experimental hypercorticism]. / Sdvigi v elektrolitnom i energeticheskom metabolizme miokarda krys pri eksperimental'nom giperkortitsizme

Experiments were conducted on 612 albino male rats; a complex study was made in the myocardium of K+, Na+, Ca2+, Mg2+, Cl-, water, creatinphosphate, inorganic phosphorus, adenylic system components. A study was made of the effect of exogenous hypercorticism created by the administration of prednisolone, hydrocortisone and DOCA on the cardiac metabolism. Potassium-sodium tissue homeostasis in the myocardium proved to be stable under these conditions. Glucocorticoid hypercorticism was characterized by a reduction of creatinphosphate and by the accumulation of inorganic phosphate. DOCA administration failed to be significantly reflected on the balance of the phosphate macroerg balance. Glucocorticosteroids caused an increase in the Mg2+ and a reduction of the Cl- level, whereas DOCA brings about an increase of Ca2+ and Cl- in the myocardium. Dosaged sharp physical load is accompanied by the K+ cumulation in the myocardium. In the case of 2-hour swimming this is combined with a "stable" condition of the energy processes. When swimming is continued up to 5 hours there occurs a distinct disturbance of the balance of disintegration and resynthesis of the phosphate macroergs in the cardiac muscle. Administration of the corticosteroids under study against this background produced no significant influence on the character of the shifts in the electrolyte-energy metabolism, and failed to prevent the normal course of the restorative processes in the myocardium at the immediate period after the exercises.