Subject(s)
COVID-19 , Dermatomycoses , Folliculitis , Malassezia , Critical Illness , Dermatomycoses/diagnosis , Humans , SARS-CoV-2ABSTRACT
BACKGROUND: Most of the knowledge on the prevailing dermoscopic patterns of acquired melanocytic nevi (AMV) is based on studies in Caucasians, while little research focuses on the dermoscopic variability in nevi in skin of colour. OBJECTIVE: To analyse the prevalent dermoscopic nevus patterns in subjects with a skin type (ST) V and VI. METHODS: Prospective, cross-sectional, morphological study was conducted in six clinics with enrolment of consecutive individuals with a ST V or VI. Digital dermoscopic images of selected representative AMN were assessed for dermoscopic colours, morphological patterns and pigment distribution. RESULTS: Analysis of 300 nevi from subjects with ST V and VI revealed significant differences in the nevus pattern between these two groups. The majority of nevi in ST V revealed a reticular pattern, whereas persons with ST VI more frequently exhibited a structureless pattern. Black, blue and grey were more frequent in ST VI, whereas the vast majority of nevi in ST V individuals showed dark brown colour. CONCLUSIONS: Our study provides new insights into the nevus pattern in individuals with a dark pigmentary trait, which may aid the diagnosis and management of nevi in this patients group.
Subject(s)
Color , Dermoscopy , Nevus, Pigmented/pathology , Skin Neoplasms/pathology , Skin Pigmentation , Adult , Argentina , Brazil , Cross-Sectional Studies , Female , Humans , Italy , Male , Middle Aged , Nevus, Pigmented/diagnosis , Nevus, Pigmented/epidemiology , Prevalence , Prospective Studies , Skin Neoplasms/diagnosis , Skin Neoplasms/epidemiology , TurkeySubject(s)
Antiviral Agents/therapeutic use , Cytomegalovirus Infections/complications , Opportunistic Infections/complications , Severe Combined Immunodeficiency/complications , Skin Diseases, Viral/complications , Cytomegalovirus Infections/drug therapy , Ganciclovir/therapeutic use , Humans , Male , Mouth Mucosa/virology , Oral Ulcer/virology , Skin Diseases, Viral/drug therapy , Treatment Outcome , Young AdultABSTRACT
BACKGROUND: Similar to other countries, incidence and mortality rates for cutaneous melanoma (CM) are increasing in Brazil. Resulting from centuries of ethnic mixture, the skin of the Brazilian population presents all phototypes, being progressively lighter following the increase of the latitude toward the South, where the highest incidence of melanoma is observed. Studies from the United States and Argentina in whites suggest that European ancestry could represent an important risk factor for CM in those regions. METHODS: Questionnaires from a case-control study involving 119 melanoma patients and 177 controls were reviewed for age, gender, phototype, sun exposure, photoprotection and ancestry. The patients reported the countries of ancestry of their grandparents. Data were tabulated and converted into scores that would reflect the proportion of ancestry for each country in individuals. RESULTS: Patients with German and Italian ancestry presented higher risk for CM [odds ratio (OR), 3.5; 95% confidence interval (95% CI), 1.8-6.7 and OR, 9.7; 95% CI, 3.9-24.2, respectively]. Conversely, Brazilian indigenous ancestry showed a protective effect for the development of the disease, with an OR of 0.16 (95% CI, 0.04-0.7). CONCLUSIONS: Some European ancestries, especially German and Italian, seem to be associated to a higher risk of CM in this sample from Southern Brazil. On the other hand, Brazilian indigenous ancestry presented as a protection factor against developing the tumour.