ABSTRACT
The report deals with potential of present-day techniques for radiological imaging, differential diagnosis and working out of modalities of treatment for primary and metastatic hepatic tumors. Results of complex examination (ultrasound, CT, MRI, PET using fluorine -18 FDG) of patients with benign and malignant tumors are discussed. Sensitivity and specificity of each procedure have been identified to be used in diagnosis of large-size tumors.
Subject(s)
Liver Neoplasms/diagnostic imaging , Magnetic Resonance Imaging , Positron-Emission Tomography , Tomography, X-Ray Computed , Adult , Aged , Diagnosis, Differential , Female , Fluorodeoxyglucose F18 , Humans , Liver Diseases/diagnostic imaging , Liver Neoplasms/secondary , Liver Neoplasms/therapy , Magnetic Resonance Imaging/methods , Male , Middle Aged , Positron-Emission Tomography/methods , Radiopharmaceuticals , Sensitivity and Specificity , Tomography, X-Ray Computed/methods , UltrasonographyABSTRACT
The study involved 207 patients with large-size tumors. Results of 18FDG PET pointed to the basic factor of malignant transformation--foci of enhanced accumulation of radiological medicinal substances. Absence of ultrasound and CT-based evidence of such pathological accumulations contributed to interpretation of changes as benign ones. The effectiveness of chemotherapy was assessed by tumor metabolic response to treatment given at the time of 18FDG PET examination.
Subject(s)
Fluorodeoxyglucose F18 , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/therapy , Positron-Emission Tomography , Radiopharmaceuticals , Adult , Aged , Female , Fluorodeoxyglucose F18/metabolism , Humans , Liver Neoplasms/metabolism , Liver Neoplasms/pathology , Liver Neoplasms/secondary , Male , Middle Aged , Positron-Emission Tomography/methods , Predictive Value of Tests , Radiopharmaceuticals/metabolism , Treatment OutcomeABSTRACT
The paper describes 12 years' experience in using positron emission tomography (PET) at the Russian Research Center of Radiology and Surgical Technologies to detect cancer, cardiac, and psychoneurological diseases, to make their differential diagnosis, and to evaluate the efficiency of their treatment. It shows the capacities of PET using various radiopharmaceutical agents in a broad spectrum of the above abnormalities and defines prospects for further development of the technique.
