ABSTRACT
La estadificación quirúrgica laparoscópica asociada a la histerectomía vaginal constituye un método alternativo de tratamiento del carcinoma de endometrio. El tiempo laparoscópico incluye la práctica de lavados peritoneales, la linfadenectomía y, en mayor o menor grado, la asistencia laparoscópica a la histerectomía vaginal. A causa del seguimiento limitado en muchos casos, todavía no están bien definidos los criterios acerca de las indicaciones y contraindicaciones del procedimiento. El papel de la laparoscopia en el tratamiento del cáncer de endometrio sólo podrá ser determinado cuando se disponga de estudios prospectivos y de resultados a largo plazo. (AU)
Subject(s)
Carcinoma, Endometrioid/history , Carcinoma, Endometrioid , Laparoscopy , Hysterectomy, Vaginal/methods , Lymph Node Excision/methodsABSTRACT
Seventeen patients with endometrioid carcinoma of the ovary were studied in order to establish clinical, surgical and histological prognostic factors. Disease recurred in 7 cases (41%) and statistically correlation was found between presence of ascites above 200 ml, advanced stage of the disease, low level of cellular differentiation and peritoneal disease and/or a residual tumour after surgery. No correlation was found between age at presentation, menopausal status, size of tumour or bilaterality. The estimated survival rate for 5-years was placed between 40%-50%. Pathological study found associated endometrioid disease in 3 cases (20%) (2 adenocarcinomas, 1 hyperplasia with atypias), and ovarian endometriosis in 2 cases (12%). Furthermore, two extremely rare cases are reported: clinical presentation of paraneoplastic dermatomiositis and recurrence at the laparoscopic puncture site.
Subject(s)
Carcinoma, Endometrioid/complications , Carcinoma, Endometrioid/pathology , Ovarian Neoplasms/complications , Ovarian Neoplasms/pathology , Adult , Aged , Carcinoma, Endometrioid/surgery , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/epidemiology , Neoplasm Staging , Ovarian Neoplasms/surgery , PrognosisABSTRACT
Gynadroblastoma is an extremely rare tumour of the ovary containing both a granulosa cell and a Sertoli-Leydig cell tumour. We report a case of gynandroblastoma of the right ovary Stage IA (FIGO) in a 15-year-old girl. Microscopically, the tumour composed predominantly of granulosa cells with a minoritary component, although more than 10%, of Sertoli cells. The present knowledge about its nature, function and behaviour are reviewed.
Subject(s)
Neoplasms, Gonadal Tissue/pathology , Ovarian Neoplasms/pathology , Adolescent , Antigens, Tumor-Associated, Carbohydrate/analysis , Female , Granulosa Cells/pathology , Humans , Male , Neoplasm Staging , Sertoli Cells/pathologyABSTRACT
Thirty-one patients with ovarian tumors of low malignant potential (borderline) treated between 1982 and 1992 have been reviewed. The mean age was 46.3 years (range: 20-77). Postsurgical stage (FIGO) obtained was: I 24 (77.4%), II 2 (6.5%) and III 4 (12.9%). Histologic subtypes were mucinous 16 (48.3%), serous 12 (38.7%), endometrioid 1 (3.2%) and mixed type 2 (6.5%). All patients underwent primary surgical treatment and conservative surgery (unilateral oophorectomy) was performed in 8 (25.8%) young patients at early-stage. Ovarian tumors were bilateral in 3 (9.7%) of cases; peritoneal implants were found in 4 (14.3%) cases; and retroperitoneal nodal involvement was confirmed in 1 (3.2%) case. Only patients at advanced-stage received adjuvant chemotherapy (cisplatin-based). The survival rate obtained at 5 years was 100% for Stage IA, 96% for early-stage (I/II), and 75% for advanced-stage (III). Results were evaluated in order to assess clinicopathologic features, surgical approach, and outcome of borderline ovarian tumors.
