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2.
Immunol Allergy Clin North Am ; 43(3): 593-612, 2023 08.
Article in English | MEDLINE | ID: mdl-37394262

ABSTRACT

The spondyloarthritides are a diverse group of distinct yet interrelated disease processes with overlapping clinical features. They are ankylosing spondylitis, reactive arthritis, inflammatory bowel disease-associated arthritis, and psoriatic arthritis. Genetically, these disease processes have been linked by the presence of HLA-B27. They manifest with axial and peripheral symptoms, such as inflammatory back pain, enthesitis, oligoarthritis, and dactylitis. The onset of symptoms can begin before the age of 45; however, because of the wide range of signs and symptoms, diagnosis can be delayed, leading to unchecked inflammation, structural damage, and later, restriction in physical mobility.


Subject(s)
Arthritis, Psoriatic , Arthritis, Reactive , Inflammatory Bowel Diseases , Spondylarthritis , Spondylitis, Ankylosing , Humans , Spondylarthritis/diagnosis , Spondylarthritis/etiology , Spondylitis, Ankylosing/diagnosis , Spondylitis, Ankylosing/etiology , Arthritis, Psoriatic/diagnosis , Arthritis, Reactive/diagnosis , Inflammatory Bowel Diseases/diagnosis , Inflammatory Bowel Diseases/etiology
4.
Emerg Med Clin North Am ; 40(1): 159-178, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34782086

ABSTRACT

The spondyloarthritides are a diverse group of distinct yet interrelated disease processes with overlapping clinical features. They are ankylosing spondylitis, reactive arthritis, inflammatory bowel disease-associated arthritis, and psoriatic arthritis. Genetically, these disease processes have been linked by the presence of HLA-B27. They manifest with axial and peripheral symptoms, such as inflammatory back pain, enthesitis, oligoarthritis, and dactylitis. The onset of symptoms can begin before the age of 45; however, because of the wide range of signs and symptoms, diagnosis can be delayed, leading to unchecked inflammation, structural damage, and later, restriction in physical mobility.


Subject(s)
Spondylarthritis/physiopathology , Humans , Spondylarthritis/diagnosis , Spondylarthritis/therapy
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