Myelopathy Associated with Rapid Progression of a Dystrophic Neurofibromatosis-1 Curve - A Case Report and Review of Literature.

Introduction: Thoracic myelopathy in neuro fibromatosis-1 (NF-1) is most commonly due to intra-spinal neurofibromas/dumb-bell tumors/intra-canal rib head penetration (RHP) causing cord compression. However, acute thoracic myelopathy due to rapid progression of the kyphoscoliotic curve alone in NF-1 without a significant spinal cord compression occurs very rarely. This case report discusses our experience with one such patient and we also discuss intraoperative and post-operative challenges encountered with this patient and a rare complication of hemothorax postoperatively. Case Report: A 15-year-old male presented to the clinic after being lost to follow-up for 4 years with a rapid acute deterioration of dystrophic curve and no myelopathic symptoms (Scoliosis - 65°, Kyphosis - 77°). His subsequent examination in 6 weeks showed acute development of myelopathic gait with right ankle and extensor hallucis longus weakness. He was admitted for halo gravity traction for 6 weeks and a single-stage posterior instrumentation with excision of rib heads at the apex was planned. Postoperatively, the patient developed massive left hemothorax and loss of power in both lower limbs at day 2. He subsequently regained full power and complete resolution of myelopathic symptoms at the end of 9- month follow-up with a satisfactory alignment of spine in the follow-up X-rays. Conclusion: Acute onset of myelopathy is a rare and uncommon finding with a rapid deterioration of dystrophic curve alone without any major spinal cord compromise. Early detection of dysplastic changes with early aggressive surgical management and deformity correction is necessary with dystrophic NF-1 curves to prevent pre-operative and post-operative morbidities.

White cord syndrome following posterior decompression and fusion for severe OPLL and an acute traumatic cervical injury - A case report and review of literature.

Background: White cord syndrome (WCS) refers to the observation of intramedullary hyperintensity due to edema/ischemia and swelling on postoperative T2-weighted MRI sequences in the setting of unexplained neurological deficits after cervical spinal cord decompression. Pathophysiologically, WCS/reperfusion injury (RPI) occurs due to oxygen derived free radicals as a result of acute reperfusion or direct trauma from blood flow itself. Intraoperative neurophysiologic monitoring (IONM) can give early warning and detect neurologic deficits. Here, we are presenting a case of a patient who had a chronic severe ossification of posterior longitudinal ligament (OPLL) of cervical cord, underwent decompressive surgery, and developed quadriplegia postoperatively without any perceptible iatrogenic cord trauma, documented by IONM and postoperative MRI with classical signs of WCS. Case Description: A 63-year-old male presented with low velocity fall at home followed by quadriparesis. X-ray images on presentation showed C6 fracture and local kyphosis. MRI images showed that there is marked spinal canal stenosis from C2 down to C4 due to OPLL with intrinsic signal changes in the cord. On decompression, motor-evoked potential signals were not present below C4. Immediate postoperative MRI was done to rule out any compressive pathology. MRI showed T2 hyperintensity of the cord at C3 level with cord edema. No evidence of epidural hematoma or other compressive lesion was found and the diagnosis of WCS/RPI was established. Conclusion: WCS is essentially a diagnosis of exclusion. Very rarely, patients sustain severe/new neurological deficits postoperatively attributed to WCS. Unless, this is confirmed postoperatively with classical MRI signs of intramedullary hyperintensity, the diagnosis should not be invoked.

Prospective Randomized Controlled Trial to Study the Effect of Local Steroids in the Retropharyngeal Space After Anterior Cervical Discectomy and Fusion.

STUDY DESIGN: Prospective randomized controlled trial. OBJECTIVE: To study the effect of local steroids in the retropharyngeal space after anterior cervical discectomy and fusion (ACDF) in reducing prevertebral soft-tissue swelling (PSTS) and complications associated with it. METHODS: A total of 50 consecutive patients operated with ACDF were double-blinded randomized into 2 groups: steroids (25) and control (25). Triamcinolone in collagen sponge was used in the steroid group and normal saline in gelatin sponge in the control group. Patients' lateral radiographs were taken on the immediate postoperative day; days 2, 4, and 6; at 2 weeks; and 2 and 6 months postoperatively. The PSTS ratio at C3 to C7 and PSTS index were calculated. Patients were clinically evaluated using the Visual Analogue Scale (VAS) score for odynophagia and radiating pain, modified Japanese Orthopedic Association Score (mJOA), and Neck Disability Index (NDI). RESULTS: PSTS showed a significant reduction in the steroid group as compared with the control group on the immediate postoperative day; days 2, 4, and 6; and at 2 weeks. However, at 2 and 6 months, PSTS remained the same. VAS score for odynophagia also showed a significant difference between the 2 groups on the immediate postoperative day; days 2, 4, and 6; and 2 weeks postoperatively, with no significant difference at the 2- and 6-month follow-up. mJOA and NDI showed no significant difference between the 2 groups at the 2- and 6-month follow-up. CONCLUSION: Use of retropharyngeal steroids helps in reducing the postoperative odynophagia on a short-term basis without any complication.

Golden Wires and Rectangle: A Cost-Effective Treatment for Tuberculosis of the Thoracic Spine.

STUDY DESIGN: This was a retrospective study. PURPOSE: The purpose of this study was to compare the functional outcome and cost of surgery for tuberculosis (TB) of the thoracic spine between two commonly used fixation modalities "pedicular screws and rods" and "Hartshill loop rectangle and sublaminar wires." OVERVIEW OF LITERATURE: TB is a common ailment in Asia. Surgical indications have remained almost unchanged since the middle-path regimen was advocated by Tuli. Pedicle screws and Hartshill loop rectangle with sublaminar wires are the two common fixation techniques used. MATERIALS AND METHODS: This retrospective observational study was performed at a single tertiary center. Patients were divided into two groups depending on the method of fixation (pedicle screw rod/Hartshill loop rectangle and sublaminar wires). All patients were evaluated preoperatively by X-rays and magnetic resonance imaging. Patients were assessed clinically by preoperative and postoperative neurology and Visual Analog Scale score and radiologically assessed by the K angle. These variables were separately compared in both the groups. RESULTS: The functional outcomes of Hartshill loop rectangle and sublaminar wire fixation and that of pedicular screw fixation were comparable. Hartshill loop rectangle and sublaminar wire fixation was found to be more cost-effective. CONCLUSION: Hartshill loop rectangle and sublaminar wire fixation gets purchase over the posterior column structures alone when compared to pedicle screws which have a 3-column hold. However, when combined with meticulous neural decompression and skillful preparation of osteogenic bed with autologous strut grafting and additional onlay grafting, it gives overall adequate stabilization of the column with functional outcome comparable to pedicular screw and rod fixation with additional benefit of cost-effectiveness. Although Hartshill loop rectangle and sublaminar wire fixation is less commonly used now, it has a special place in the management of TB, especially in a resource-poor setting like some countries of Asia.

Posterior Cervical Interbody Fusion - Single-Stage Approach of Anterior Reconstruction and Posterior Stabilization: A Case Report and Review of Literature.

The success and popularity of the transforaminal approach in the lumbar spine have been made possible by the routine use of pedicle screws in the lumbar spine. Transforaminal approach in the cervical spine can give access to the disc and the vertebral body anteriorly and avoid an additional anterior approach in certain clinical situations. A case of cervical spine trauma was managed by this approach. Technical details and difficulties faced were analyzed in this article. Transforaminal approach in the lower cervical spine, though has a learning curve, seems to be a feasible technique along with the use of cervical pedicle screws. The safety and reproducibility of the approach need to be substantiated with a larger study. Further, this procedure can avoid additional anterior surgery in certain situations in the cervical spine.

Computed Tomography-based Analysis of Tibial Tuberosity-Trochlear Groove Distance in Indian Population.

Aim To study the tibial tuberosity-trochlear groove distance (TT-TG) in normal Indian population and the variation of the same in relation to tibial size using computed tomography (CT) of knee. Methods CT of 100 knees (62 males and 38 females) were assessed. TT-TG distance and maximal medio-lateral (MML) distance of tibia was measured on axial CT scans. The modified TT-TG (mTT-TG) was calculated as the ratio of TT-TG and MML. Results The average TT-TG distance was 13.01 (±2.84) mm for the entire group with males and females having 12.82 (±2.95) and 13.32 (±2.66) mm, respectively (p > 0.05). The MML distance was 75.99 (±3.78) and 66.77 (±4.33) mm for males and females, respectively (p < 0.05). The average modified TT-TG was 0.18 ± 0.04. The TT-TG distance of Indian knees was similar to values obtained in Caucasian knees and higher than other Asian knees (p < 0.05). Conclusion The average TT-TG distance in Indian population is 13.01 mm, with no difference between males and females. The ML/TT-TG ratio was 0.18. The TT-TG distance in Indian population is found to be similar to the Western population and significantly higher than other Asian population.

Anterior Release and Anterior Reconstruction for a Neglected Osteoporotic Odontoid Fracture.

A 70 years old lady presented to us with history of a fall 3 months prior. She had suffered a type 2 odontoid fracture with atlantoaxial dislocation, that was not reducible by traction. She had symptoms of neck pain with inability to hold the neck upright. The patient was subsequently planned for anterior release and reduction of odontoid fracture dislocation with posterior stabilization in the same sitting. The patient was treated with cervical skeletal traction and immobilized. However, she developed occipital sore during the period and was mobilized with brace after which she developed myelopathic symptoms and gait disturbance due to the collapse of fracture segment. The patient was planned for anterior release and fixation with contoured reconstruction plate fixing C1 lateral mass to the lateral mass on the right side and C1 lateral mass to C2 body on the left side primarily with distraction of the C1-C2 joint by autologous tricortical iliac bone graft. The posterior stabilization was planned after healing of the sore, and the patient was counseled for the same. However, the patient was lost on follow-up and returned at 3-month postoperative period with collapse of the graft, resubluxation of C1-C2 segment, and failure of anterior fixation. The standard modality of treatment for such cases includes an anterior release of contracted soft tissues and ligaments and posterior stabilization with fusion in a single setting. However, it is the posterior fixation that stabilizes the fracture and prevents it from redislocation. Anterior fixation as a stand-alone treatment in osteoporotic bone has high risks of failure due to severe posterior tensile stresses. This article describes the importance of posterior fixation in osteoporotic bone based on our experience.