Subject(s)
Amyloidosis/pathology , Adolescent , Adult , Aged , Amyloidosis/etiology , Amyloidosis/metabolism , Anemia/etiology , Child , Collagen Diseases/complications , Female , Humans , Male , Middle Aged , Multiple Myeloma/complications , Proteinuria/etiologySubject(s)
Tuberculosis, Lymph Node/diagnosis , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Retrospective StudiesSubject(s)
Histiocytoma, Benign Fibrous/pathology , Osteitis Deformans/pathology , Precancerous Conditions/pathology , Soft Tissue Neoplasms/pathology , Aged , Buttocks , Histiocytoma, Benign Fibrous/diagnostic imaging , Humans , Male , Osteitis Deformans/diagnostic imaging , Radiography , Soft Tissue Neoplasms/diagnostic imagingSubject(s)
Liver/pathology , Aged , Diagnosis, Differential , Female , Hepatomegaly/pathology , Humans , Hyperplasia , Liver Cirrhosis/diagnosis , Liver Regeneration , Splenomegaly/pathologySubject(s)
Carcinoma, Small Cell/secondary , Hepatic Encephalopathy/etiology , Liver Neoplasms/secondary , Lung Neoplasms , Aged , Humans , MaleABSTRACT
1 Forty-one patients with essential hypertension, stages I, II, and III, were treated with captopril alone or in combination with hydrochlorothiazide. Forty two percent were responsive to captopril alone, while the remaining 58% also required the diuretic. The need for the diuretic was related to the phase of hypertension. 2 There was no significant relation between drug response and plasma renin activity. Serum concentrations of creatinine and potassium remained normal, and there were no pathological changes in serum glucose, cholesterol, uric acid concentrations, erythrocyte count, packed cell volume, haemoglobin, or heart rate. 3 Captopril was well tolerated. One patient developed a rash and another ageusia, which disappeared spontaneously. A third, who was also taking allopurinol, developed leucopenia but it disappeared after treatment was withdrawn. There were no cases of proteinuria attributable to captopril; and proteinuria disappeared in four of five patients who were proteinurin before the start of treatment. 4 These findings suggest that doses of captopril of 150 mg to 300 mg (with or without a diuretic) may be adequate for controlling the blood pressure of most patients with essential hypertension.
Subject(s)
Captopril/therapeutic use , Hypertension/drug therapy , Proline/analogs & derivatives , Adult , Blood Pressure/drug effects , Captopril/adverse effects , Drug Therapy, Combination , Female , Heart Rate/drug effects , Humans , Hydrochlorothiazide/administration & dosage , Male , Middle Aged , Renin/bloodSubject(s)
Granuloma/etiology , Liver Diseases/etiology , Q Fever/complications , Humans , Male , Middle AgedSubject(s)
Ascites/etiology , Polyarteritis Nodosa/complications , Serositis/etiology , Adult , Female , Humans , MaleABSTRACT
The case histories of 1200 patients admitted to our hospital over a 20 month period were reviewed to determine the degree, frequency and cause of dissociated cholestasis as a biological syndrome. Patients were divided into two groups: group I with 80 cases, included all patients whose gamma-GT levels were more than 30 mU/ml and serum-bilirubin less than 1.2 mg/ml, with alkaline phosphatase levels between 90-180 mU/ml. Group II included those with alkaline phosphatase levels higher than 180 mU/ml (57 cases). All over incidence of dissociated cholestasis was 13.82%. Main causes in group I were infectious diseases, mainly pneumonias and urinary infections and congestive cardiac failure. In group II, neoplasias such as Hodgkin's disease and epithelial metastases and obstructions of the biliary tract such as vesicular or choledocal litiasis were the main causes. Transaminase levels underwent variable increases according to the different entities, without there being any difference between the two groups. The physiopathology as well as the anatomopathological aspects which could originate the syndrome are discussed.
