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1.
Nat Prod Commun ; 6(5): 699-700, 2011 May.
Article in English | MEDLINE | ID: mdl-21615035

ABSTRACT

The essential oil from the fruits of Vismia baccifera Triana & Planch. (Gutttiferae), collected in June 2009, was analyzed by GC/MS. A yield of 0.6% oil was obtained by hydrodistillation. Twenty-seven components were identified by comparison of their mass spectra with those in the Wiley GC-MS Library data base. The major components were trans-cadin-l1,4-diene (36.6%), cis-cadin-1,4-diene (18.8%) and beta-caryophyllene (11.9%). The essential oil showed a broad spectrum of antibacterial activity against the important human pathogenic Gram-positive and Gram-negative bacteria Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25992), Pseudomonas aeruginosa (ATCC 27853) and Klebsiella pneumoniae (ATCC 23357) with MIC values ranging from 9 to 37 microg/mL.


Subject(s)
Anti-Bacterial Agents/chemistry , Clusiaceae/chemistry , Oils, Volatile/chemistry , Fruit/chemistry , Microbial Sensitivity Tests , Oils, Volatile/isolation & purification , Venezuela
2.
Nat Prod Commun ; 5(7): 1115-6, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20734953

ABSTRACT

Essential oils extracted by hydrodistillation from leaves and roots of Ottoa oenanthoides Kunth (Apiaceae) were analyzed by GC/MS. The oils, obtained in yields of 0.10% and 0.66%, respectively, each contained four compounds, which were identified from their mass spectra and retention indices (RI). The major compound identified was 2-methoxy-8-methyl-1,4-naphthalindione (59.9% leaves, and 62.8%, roots), followed by 7-methoxy-1-naphthol (18.3% leaves and 17.3% roots), 2-naphthalenol (18.6% leaves and 15.0% roots), and 3-methoxy-2-naphthalenol (3.1% leaves and 2.1% roots). To the best of our knowledge, this is the first time that naphthalene derivatives have been reported for any species of the Apiaceae family.


Subject(s)
Apiaceae/chemistry , Oils, Volatile/chemistry , Plant Leaves/chemistry , Plant Roots/chemistry , Venezuela
3.
Nat Prod Commun ; 4(11): 1601-4, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19967999

ABSTRACT

The essential oil from the leaves of Monticalia andicola Turcz., collected in November 2008, was analyzed by GC/MS. A yield of 0.15% oil was obtained by hydrodistillation. Thirty-six components were identified by comparison of their mass spectra with those in the Wiley GC-MS Library data base. The major components were alpha-pinene (19.6%), beta-pinene (10.5%), alpha-longipinene (6.5%), delta-3-carene (6.2%), cyperene (5.4%) and beta-phellandrene (5.2%). The antibacterial activity of the essential oil was evaluated against Gram- positive (Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212) and Gram-negative (Escherichia coli ATCC 25992, Klebsiella pneumoniae ATCC 23357, Pseudomonas aeruginosa ATCC 27853) bacteria, using the disc diffusion agar method. The results showed a broad spectrum of activity with minimal inhibitory concentration (MIC) values ranging from 10 to 150 microg/mL.


Subject(s)
Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/pharmacology , Asteraceae/chemistry , Oils, Volatile/chemistry , Oils, Volatile/pharmacology , Bacteria/drug effects , Chromatography, Gas , Gas Chromatography-Mass Spectrometry , Microbial Sensitivity Tests , Venezuela
4.
Nat Prod Commun ; 4(4): 571-2, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19476008

ABSTRACT

The essential oils from leaves of E. caracasana Boiss collected from Miyoi, Pueblo Llano, Mérida State at 1800 m above sea level and leaves of E. cotinifolia L collected from Manzano Alto-Ejido, Mérida State at 1520 m were analyzed by GC/MS. Beta-Caryophyllene (33.7 %), alpha-humulene (18.8 %) and aromadendrene (8.4 %) were the major constituents of E. caracasana oil, whereas those of E. cotinifolia oil were beta-caryophyllene (39.3 %), germacrene-D (21.5 %) and alpha-copaene (9.3 %).


Subject(s)
Euphorbia/chemistry , Oils, Volatile/chemistry , Gas Chromatography-Mass Spectrometry , Oils, Volatile/isolation & purification , Plant Leaves/chemistry , Venezuela
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