1.
Org Lett
; 16(15): 4001-3, 2014 Aug 01.
Article
in English
| MEDLINE
| ID: mdl-25033232
ABSTRACT
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tartaric acid. Key reactions in the synthesis include the Ley's dithiaketalization of an alkynone derived from the bis-Weinreb amide of tartaric acid, Boord olefination, and ring-closing metathesis of an acrylate ester.