ABSTRACT
Background The surgical removal of mandibular third molars is one of the most common procedures in dentistry. Researchers have extensively studied the treatment of postoperative sequelae such as pain, edema, trismus, and alveolar osteitis throughout the past six decades. Many approaches have been used to address clinical difficulties after third molar surgery, including various flap designs and irrigating solutions. The aim of this study was to compare the effects of three irrigating solutions, hydrocortisone, povidone-iodine, and normal saline, on pain, trismus, and edema following surgical removal of the impacted mandibular third molar. Methodology The study involved 105 participants who required surgical extraction of mandibular third molars. The patients' ages ranged from 18 to 40 years, and they fulfilled the inclusion criteria. Using a simple random sampling technique, they were divided into three groups (group 1: hydrocortisone, group 2: povidone-iodine, group 3: normal saline). The parameters evaluated were edema, pain, and trismus on the second and seventh postoperative days. All data were input into Microsoft Excel (Microsoft® Corp., Redmond, USA) worksheets and analyzed using Stata 17.0 (StataCorp LLC, College Station, USA). The visual analog scale (VAS) score was used to measure postoperative pain, and postoperative swelling was measured using linear measurements from four fixed anatomical points and compared to preoperative values. To assess trismus, the inter-incisal distance was measured in millimeters with a caliper. A p-value of <0.01 was considered statistically significant. Results The mean VAS score for pain in group 1 was lower than the other two groups. The effect of group 1 was significant on the second postoperative day but insignificant on the seventh postoperative day for swelling. The effect of all three groups on trismus was significant on the second and seventh days. Conclusions Hydrocortisone as an irrigating solution showed promising results in managing postoperative swelling in the first 48 hours, but its effect gradually declined by the seventh postoperative day. Additionally, it was effective in controlling postoperative pain and trismus. This suggests that utilizing hydrocortisone as an irrigating solution, compared to povidone-iodine, has been proven to be a significantly effective option in reducing postoperative pain, edema, and trismus resulting from the surgical removal of impacted teeth.
ABSTRACT
BACKGROUND: Globally 220 countries and territories are affected and cases of COVID-19 have increased by 8% resulting in 3.6 million new cases. The most common symptoms include fever, cough, loss of taste or smell, headache and mortality rate was uncertain. The objective of this study is to know the clinical profile and outcomes of COVID-19 positive patients. METHODOLOGY: A Cross-Sectional Study was conducted for 2 months (October-December 2020) among 727 COVID 19 positive patients residing in the field practice area of 4 health centers. Details regarding medical history, exposure history, underlying co-morbidities, symptoms, signs clinical features and outcomes (i.e, cured, mortality, and length of stay) were obtained. RESULTS: The mean age of participants was 41 ± 17 years, 59.28% were males, 40.71% were females. A significant association was found between age, family history of disease, co-morbid disease, medication history, smoking habit, alcohol consumption, type of symptoms, isolation type, treatment given with outcomes (P < 0.05). Subjects with previous history of medication (HR, 2.749; 95% CI 1.0774-7.015), and those who had symptoms (HR, 3.6446; 95% CI1.0280-12.921) were associated with increased risk of death as compared to others. CONCLUSION: COVID-19 positive was found in 56% of patients, they were less severe and improved with medication and deaths were found in 3.85% of patients. Fever was noted in only 15.72% of patients, gastrointestinal symptoms in 1.22% and respiratory symptoms in 14.74% of patients. Participants with older age were significantly associated with complications and those with co-morbidities were significantly associated with death on multinominal logistic analysis.
