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Hum Exp Toxicol ; 39(6): 765-772, 2020 Jun.
Article in English | MEDLINE | ID: mdl-31965860

ABSTRACT

Severe carbon monoxide (CO) poisoning causes fulminant deaths in common environment as well as neurological sequelae to survivors. Prevention of delayed neurological syndrome (DNS) after exposure to CO, the most important sequela, is based up to date on hyperbaric oxygen administration. Nevertheless, its use remains controversial due to the lack of evidence regarding its efficacy. The aim of this review is to report therapies under investigation for preventing or improving DNS, some of them with promising results in humans.


Subject(s)
Carbon Monoxide Poisoning/therapy , Neurotoxicity Syndromes/prevention & control , Oxygen Inhalation Therapy , Animals , Carbon Monoxide Poisoning/complications , Carbon Monoxide Poisoning/drug therapy , Humans , Neurotoxicity Syndromes/etiology
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