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1.
Biopreserv Biobank ; 21(4): 318-326, 2023 Aug.
Article in English | MEDLINE | ID: mdl-36099204

ABSTRACT

Background: Biobanks that intend to serve as high-performing and stable elements of an innovative research ecosystem must have an established system for regular measurement and evaluation using appropriately set indicators. The main objective of this study was to provide a comprehensive overview of indicators in the context of biobanking, with new perspectives to highlight the existence of numerous options and introduce indicators that could help overcome problems associated with the difficult assessment of the impact of biobanks. Methods: A literature review was performed to identify publications relevant to the topic of indicators in biobanking. The Web of Science Core Collection and PubMed databases were searched using specific keywords. In addition, three articles that focused on indicators designed for the evaluation of research infrastructures were included in the review. Results: Based on the scientific literature for the biobanking field, many types of quantitative and qualitative indicators exist. They are mainly related to the quantity and quality of data and samples, their distribution, the monitoring of research projects, and subsequent publication outputs. The indicators identified in the biobanking literature primarily focus on the outcome, not the impact. Conclusions: Indicators identified in the biobanking literature may be further expanded with suggestions designed for other types of research infrastructures, while considering the context where biobanks operate and the needs of individual biobanking stakeholders. The establishment of a comprehensive monitoring system that captures all necessary elements is crucial for modern biobanks.


Subject(s)
Biological Specimen Banks , Biomedical Research , Ecosystem
2.
Res Microbiol ; 156(9): 932-43, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16085397

ABSTRACT

Microorganisms were isolated from lignite freshly excavated in the Záhorie coal mine (southwestern Slovakia) under conditions excluding contamination with either soil or air-borne microorganisms. The isolates represented both Prokarya and Eukarya (fungi). All were able to grow on standard media, although some microorganisms were unstable and became extinct during storage of coal samples. Bacteria belonged to the genera Bacillus, Staphylococcus, and Rhodococcus, according to both morphological criteria and ITS sequences. Several bacterial isolates were resistant to antibiotics. The presence of anaerobic bacteria was also documented, although they have not yet been identified. Fungal isolates were typified by using their ITS sequences. They belonged to the genera Trichoderma (Hypocrea), Penicillium, Epicoccum, Metarhizium (Cordyceps), and Cladosporium. Several fungi produced compounds with antibiotic action against standard bacterial strains. The evidence for the presence of microorganisms in native lignite was obtained by means of fluorescence microscopy, scanning electron microscopy, and electron microprobe analysis. Results demonstrated that microorganisms were able to survive in the low-rank coal over a long time period.


Subject(s)
Bacteria/classification , Bacteria/isolation & purification , Coal/microbiology , Fungi/classification , Fungi/isolation & purification , Mining , Anti-Bacterial Agents/biosynthesis , Anti-Bacterial Agents/pharmacology , Antibiosis , Bacillus/classification , Bacillus/isolation & purification , Bacteria, Anaerobic/isolation & purification , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , DNA, Ribosomal Spacer/chemistry , DNA, Ribosomal Spacer/genetics , Drug Resistance, Microbial , Electron Probe Microanalysis , Microscopy, Electron, Scanning , Microscopy, Fluorescence , Molecular Sequence Data , Rhodococcus/classification , Rhodococcus/isolation & purification , Sequence Analysis, DNA , Slovakia , Staphylococcus/classification , Staphylococcus/isolation & purification
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