ABSTRACT
We present the case report of a patient with a history of lung cancer in whom the typical pattern of hypertrophic osteoarthropathy was seen on bone scintigraphy. We discuss the etiologies, pathophysiology, and management of this entity.
Subject(s)
Bone and Bones/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Humans , Male , Middle Aged , Osteoarthropathy, Secondary Hypertrophic/pathology , Radionuclide ImagingABSTRACT
We present a patient with spleen uptake on bone scanning that was due to sickle cell disease. We also discuss other etiologies for this finding.
Subject(s)
Anemia, Sickle Cell/diagnostic imaging , Anemia, Sickle Cell/metabolism , Bone and Bones/diagnostic imaging , Spleen/diagnostic imaging , Spleen/metabolism , Technetium Tc 99m Medronate/metabolism , Technetium Tc 99m Medronate/pharmacokinetics , Bone and Bones/metabolism , Female , Humans , Incidental Findings , Radiopharmaceuticals , Tomography, Emission-Computed, Single-Photon/methods , Young AdultABSTRACT
In this report, we present a case of complex regional pain syndrome in a 55-y-old woman in whom the diagnosis was made on the basis of the bone scan findings. We also discuss the typical and atypical scintigraphic presentations of this entity, including pathophysiology and management.
Subject(s)
Complex Regional Pain Syndromes/diagnostic imaging , Hand Bones/diagnostic imaging , Technetium Tc 99m Medronate , Tomography, Emission-Computed, Single-Photon/methods , Wrist Joint/diagnostic imaging , Diagnosis, Differential , Female , Humans , Middle Aged , RadiopharmaceuticalsABSTRACT
On brain perfusion SPECT, a primary brain lesion presents as a localized defect that corresponds to the mass lesion. (99m)Tc-HMPAO images generally show a focal defect in the region of abnormality, whether containing necrotic tissue, recurrent tumor, or both. Further characterization with MR imaging is needed to confirm the diagnosis, as demonstrated in this case report.
Subject(s)
Magnetic Resonance Imaging , Meningioma/diagnostic imaging , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon , Adult , Female , Humans , Meningioma/pathologyABSTRACT
Lumbosacral transitional vertebra (LSTV) is a congenital anomaly of the lumbosacral junction. The association between back pain and LSTV is controversial; however, in our patient the symptoms localized to a hemisacralized left transverse process of L5. LSTV should be included in the differential diagnosis in young patients with lower back pain, and scintigraphic imaging should be considered for diagnostic purposes.
Subject(s)
Multimodal Imaging , Spine/abnormalities , Technetium Tc 99m Medronate , Tomography, Emission-Computed, Single-Photon , Tomography, X-Ray Computed , Adolescent , Female , Humans , Lumbosacral Region/diagnostic imaging , Spine/diagnostic imagingABSTRACT
We present a case demonstrating how correlative imaging with (123)I-ioflupane SPECT and (18)F-FDG PET can be used to help make the diagnosis of Lewy body disease more specific.
Subject(s)
Fluorodeoxyglucose F18 , Lewy Body Disease/diagnostic imaging , Nortropanes , Positron-Emission Tomography/methods , Radiopharmaceuticals , Tomography, Emission-Computed, Single-Photon/methods , Aged, 80 and over , Brain/diagnostic imaging , Diagnosis, Differential , Humans , MaleABSTRACT
Stress injury is a common cause of exercise-induced anterior shin pain. It is important to distinguish between the various causes of stress injury in a timely manner in order to optimize favorable treatment outcomes. Here, we will discuss a case of medial tibial stress syndrome, or shin splints, as one of the causes of shin pain, as well as how to approach shin pain for a successful diagnosis.
Subject(s)
Medial Tibial Stress Syndrome/complications , Medial Tibial Stress Syndrome/diagnostic imaging , Pain/etiology , Running , Adolescent , Diagnosis, Differential , Female , Humans , Pain/diagnostic imaging , Radionuclide Imaging , Radiopharmaceuticals , Technetium Tc 99m Medronate , Tibia/diagnostic imaging , Tibia/injuriesABSTRACT
We present a case illustrating how cerebral perfusion scintigraphy can be used to assist in crucial medical decision making in the intensive care setting for patients who are maintained on life support but are clinically suspected to have brain death. Cerebral perfusion scintigraphy can confirm brain death but cannot be used to diagnose it. (99m)Tc-HMPAO and (99m)Tc-ethylcysteinate dimer are the preferred imaging agents since they cross the blood-brain barrier.
Subject(s)
Brain Death/diagnostic imaging , Perfusion Imaging , Child, Preschool , Female , Humans , Life Support CareABSTRACT
We present a patient with a remote history of splenectomy and recent hemicolectomy for colon adenocarcinoma. On routine surveillance chest/abdomen/pelvis CT, a lesion suspicious for hepatic metastasis was identified. Followup MRI was inconclusive. For more specific tissue characterization, imaging with Tc-99m heat-damaged RBCs was obtained to guide further patient management. Tc-99m-labeled, heat-damaged RBC scintigraphy is an underused modality that is highly specific for detecting ectopic or accessory splenic tissue. There have been many reported cases of patients undergoing unnecessary biopsies or laparotomies to remove suspicious masses that were subsequently found to be ectopic splenic tissue.
Subject(s)
Molecular Imaging , Nuclear Medicine , Radiotherapy/methods , Societies, Scientific , Thyroid Diseases/radiotherapy , Child , Documentation , Female , Follow-Up Studies , Humans , Iodine Radioisotopes/adverse effects , Iodine Radioisotopes/therapeutic use , Pregnancy , Quality Control , Radiotherapy/adverse effects , Radiotherapy/instrumentation , Research Report , SafetyABSTRACT
PURPOSE: Proper identification of the cardiac cycle is essential for gated SPECT myocardial perfusion imaging. We have developed an alternate method of ECG for gating, that is, using the peripheral pulse wave (PW) as the triggering signal for gated SPECT acquisition. The aim of this study is to compare the use of this method of gating with the standard ECG trigger. METHODS: We tested the PW triggering by comparing it with the ECG trigger. We evaluated 33 patients (25 males, 8 females), average age of 61 years (39-80) referred for stress myocardial perfusion imaging. Data from all patients were acquired twice and were processed by CEqual and QGS software. We compared the left ventricular ejection fraction (LVEF), end-diastolic and end-systolic volumes (EDV, ESV). Paired t test and Pearson correlation coefficient were used for comparison. RESULTS: The mean LVEF, EDV, and ESV calculated with the ECG trigger were 0.52, 120, and 64, respectively, those with the pulse-wave trigger were 0.48, 126, and 71, respectively. Mean paired difference for LVEF was -0.034 (P<0.001), for EDV 5.9 (P=0.012), and for ESV 7.9 (P<0.001). Pearson correlation coefficient for LVEF was 0.955, for EDV 0.987, and for ESV 0.991 (P<0.001 for all correlations). CONCLUSION: Triggering of gated-data acquisition by the PW is feasible. Quantitative parameters of cardiac function correlate highly with those obtained from the ECG trigger and the absolute differences are not clinically significant across a wide range of values.
