Nucleus accumbens lesion does not affect schedule induced polydipsia.

Rats with lesion of nucleus accumbens were hypodipsic under free-feeding conditions. In schedule-induced polydipsia (SIP) tests conducted by reducing the rats to 70% of free-feeding body weight and delivering 60 mg bengal gram pellets on a fixed time 1-min schedule, nucleus accumbens lesions did not delay the acquisition or show a decrease in the maintenance of S.I.P.