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5.
Farmakol Toksikol ; 39(5): 635-8, 1976.
Article in Russian | MEDLINE | ID: mdl-1028597

ABSTRACT

A procedure for determining orientation reaction after Boissié et al (1964) was modified for albino rats. In determining the thresholds of acute action of phthalates and carboran in comparison with summation-threshold index, registration of spontaneous motor activity and orientation reaction according to the number of risings in a jar the proposed method is shown to be 5-10 times more sensitive.


Subject(s)
Behavior, Animal/drug effects , Motor Activity/drug effects , Orientation/drug effects , Animals , Dibutyl Phthalate/pharmacology , Diethylhexyl Phthalate/pharmacology , Psychological Tests/methods , Rats
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