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1.
Med Sante Trop ; 28(4): 434-438, 2018 Nov 01.
Article in English | MEDLINE | ID: mdl-30799833

ABSTRACT

Study the epidemiological, diagnostic, and treatment features and outcomes of necrotic breast cancer in women. This observational, longitudinal, and descriptive study covered the period from January, 2011, to the end of May, 2016 at the Surgery and Gynecology Departments of Yalgado Ouedraogo University Hospital and Schiphra Medical Center. The study included all women with necrotic breast cancers. Survival was calculated by the Kaplan Meier method and survival comparison was possible with the log-rank method. À risk of error of 0.05 was allowed. Necrotic cancer accounted for 9.1% of all breast cancers. The median age of the patients was 46 years old. The median interval before consultation was 12.4 months. The histological type was invasive ductal carcinoma in 90.8% of cases. Surgery was performed in 51 patients (52%). It was a palliative (cleaning) procedure in 92.2% of cases. Chemotherapy was performed in 28 patients. Overall survival was 61.8% at 6 months, 39.5% at 1 year, and 9.2% at 3 years. Median survival was 10 months: 13 months for women with surgery and 6 months for those without it (p<0.001). Necrotic breast cancer is still common in Ouagadougou. Surgery is the mainstay of the treatment. Survival is mediocre. It therefore seems urgent to focus on raising population awareness and organizing screening campaigns.


Subject(s)
Breast Neoplasms/pathology , Necrosis , Adolescent , Adult , Aged , Aged, 80 and over , Anemia/epidemiology , Breast Neoplasms/mortality , Breast Neoplasms/therapy , Burkina Faso , Carcinoma, Ductal, Breast , Chemotherapy, Adjuvant/statistics & numerical data , Female , Humans , Leukocytosis/epidemiology , Longitudinal Studies , Mastectomy/statistics & numerical data , Middle Aged , Palliative Care/statistics & numerical data , Time-to-Treatment , Young Adult
2.
J Med Case Rep ; 11(1): 96, 2017 Apr 08.
Article in English | MEDLINE | ID: mdl-28388964

ABSTRACT

BACKGROUND: Dermatofibrosarcoma protuberans is a rare tumor, representing about 0.1% of skin malignant tumors. It is characterized by local aggressiveness with significant potential for recurrence. Although metastasis is rare, it does occur. We report a case of a Burkinabe woman with dermatofibrosarcoma protuberans. CASE PRESENTATION: A 27-year-old Burkinabe woman consulted our institution for a recurrent scalp nodule that had been evolving for 13 years. At clinical examination, she was in good condition with a dry cough. An atrophic scarring alopecic plaque of 15-cm diameter in the right parietal region of the scalp, topped by an erythematous firm nodule measuring 3 × 2 × 2 cm, was noted, as well as a mobile nodule located in the axillary tail of the right breast. Cerebral computed tomodensitometry had not objectified the reach of the vault or the brain. A thoracic scan revealed four intrathoracic tissue masses straight to pleural touch. There were no evolutionary lesions in the abdominopelvic region. Histopathologic examination of the biopsy of the scalp nodule showed a proliferation of fibrous background, with fusiform cells carrying a storiform appearance. These cells had dark, elongated nuclei and showed some mitosis without atypia. The cells expressed CD34 intensely and diffusely. The test results were negative for PS100 and smooth muscle actin. The breast nodule showed the same profile as the scalp nodule. CONCLUSIONS: We concluded on the diagnosis of scalp dermatofibrosarcoma protuberans with breast metastasis and probable pleuropulmonary metastasis.


Subject(s)
Breast Neoplasms/secondary , Dermatofibrosarcoma/pathology , Lung Neoplasms/secondary , Neoplasm Recurrence, Local/pathology , Pleural Neoplasms/secondary , Scalp/pathology , Skin Neoplasms/pathology , Adult , Alopecia/pathology , Antigens, CD34/metabolism , Antineoplastic Agents/therapeutic use , Biopsy , Breast Neoplasms/pathology , Cough/etiology , Dermatofibrosarcoma/therapy , Female , Humans , Imatinib Mesylate/therapeutic use , Lung Neoplasms/pathology , Pleural Neoplasms/pathology , Prognosis , Skin Neoplasms/therapy , Treatment Outcome
3.
Med. Afr. noire (En ligne) ; 64(07): 393-398, 2017.
Article in French | AIM (Africa) | ID: biblio-1266264

ABSTRACT

La maladie de Ménétrier est une affection rare caractérisée par l'hypertrophie des gros plis gastriques avec un risque accru de dégénérescence. Si la cause reste inconnue, il a été mis en évidence récemment une expression du facteur de croissance épidermique sur les cellules pathologiques de la muqueuse gastrique. Une femme de 25 ans a été reçue pour des épigastralgies associées à des vomissements. L'endoscopie digestive haute évoquait une gastropathie hypertrophique ulcéro-infiltrative évocatrice de dégénérescence de maladie de Ménétrier confirmée par l'histologie (adénocarcinome peu différencié). La patiente a reçu une chimiothérapie par paclitaxel + cysplatine pour obtenir une survie de 6 mois. La Maladie de Ménétrier découverte à un stade précoce est curable. La découverte tardive chez notre patient soulève le problème de l'endoscopie digestive haute chez le sujet jeune devant toute épigastralgie persistante


Subject(s)
Adenocarcinoma , Burkina Faso , Endoscopy, Digestive System , Gastritis, Hypertrophic
4.
Med. Afr. noire (En ligne) ; 63(4): 253-256, 2016. ilus
Article in French | AIM (Africa) | ID: biblio-1266181

ABSTRACT

Le kyste trichilemmal proliférant est une tumeur annexielle cutanée bénigne rare. Des cas de transformation maligne ont exceptionnellement été rapportés. Au travers d'une revue de la littérature, nous analysons un cas de transformation maligne diagnostiqué au CHU de Brazzaville en insistant sur les caractéristiques épidémiologiques, clinico-pathologiques et les difficultés de traitement dans notre contexte d'exercice


Subject(s)
Carcinoma, Squamous Cell , Congo
5.
Carcinologie Pratique en Afrique ; 14(1): 30-33, 2015. tab
Article in French | AIM (Africa) | ID: biblio-1260267

ABSTRACT

Le cancer bronchique primitif est la deuxieme cause de mortalite dans le monde apres les pathologies cardiovasculaires. En Afrique; l'introduction de l'endoscopie a entraine l'augmentation de son 'incidence. Pour avoir une recente idee sur cette affection; nous avons decide de mener une etude retrospective et descriptive a Ouagadougou du 1er janvier 2002 au 31 decembre 2011. Ainsi avons-nous observe une preponderance masculine et un age moyen de 58 ans. La consommation moyenne de tabac a ete evaluee a 15 paquets-annee. Il y avait une predominance de l'atteinte de l'arbre bronchique droit et du carcinome epidermoide. La place du tabagisme a encore ete confirmee comme facteur etiologique


Subject(s)
Carcinoma, Bronchogenic , Lung Neoplasms/etiology , Tobacco Smoking
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