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1.
J Radiat Res ; 53(2): 264-71, 2012.
Article in English | MEDLINE | ID: mdl-22510599

ABSTRACT

The frequency distributions of the lineal energy, y, of 160 MeV proton, 150 MeV/u helium, and 490 MeV/u silicon ion beams were measured using a wall-less tissue equivalent proportional counter (TEPC) with a site size of 0.72 µm. The measured frequency distributions of y as well as the dose-mean values, y(D), agree with the corresponding data calculated using the microdosimetric function of the particle and heavy ion transport code system PHITS. The values of y(D) increase in the range of LET below ~10 keV µm(-1) because of discrete energy deposition by delta rays, while the relation is reversed above ~10 keV µm(-1) as the amount of energy escaping via delta rays increases. These results indicate that care should be taken with the difference between y(D) and LET when estimating the ionization density that usually relates to relative biological effectiveness (RBE) of energetic heavy ions.


Subject(s)
Biomimetic Materials , Heavy Ions , Linear Energy Transfer , Radiometry/instrumentation , Radiometry/methods , Equipment Design , Equipment Failure Analysis , Helium , Protons , Reproducibility of Results , Scattering, Radiation , Sensitivity and Specificity , Silicon
2.
Phys Med Biol ; 55(17): 5089-101, 2010 Sep 07.
Article in English | MEDLINE | ID: mdl-20702924

ABSTRACT

The frequency distribution of the lineal energy, y, of a 290 MeV/u carbon beam was measured to obtain the dose-weighted mean of y and compare it with the linear energy transfer (LET). In the experiment, a wall-less tissue-equivalent proportional counter (TEPC) in a cylindrical volume with a simulated diameter of 0.72 microm was used. The measured frequency distribution of y as well as its dose-mean value agrees within 10% uncertainty with the corresponding data from microdosimetric calculations using the PHITS code. The ratio of the measured dose-mean lineal energy to the LET of the 290 MeV/u carbon beam is 0.73, which is much smaller than the corresponding data obtained by a wall TEPC. This result demonstrates that a wall-less TEPC is necessary to precisely measure the dose-mean of y for energetic heavy ion beams.


Subject(s)
Carbon/chemistry , Linear Energy Transfer , Radiometry/instrumentation , Algorithms , Heavy Ions , Models, Biological , Radiometry/methods , Radiotherapy Dosage
3.
Igaku Butsuri ; 20(4): 151-158, 2000.
Article in English | MEDLINE | ID: mdl-12764240

ABSTRACT

Although low energy X-rays have been utilized for mammography, their safety in medical use is a matter of concern. Characteristics of the radiophotoluminescence glass dosimeter, GD-403, consisting of a glass element and filters, were investigated with respect to monochromatic X-rays obtained from a synchrotron radiation for personal monitoring of low energy photons. We focused on low energy X-rays ranging from 8 to 20 keV to study the linearity of the GD-403 response between photon fluence and dose equivalent. The GD-403 was placed on a tough water phantom and irradiated using an 11-15 mm x 0.1-7 mm beam for modulation of the photon fluence. The tough water phantom could be moved through a distance of 110-150 mm with a stepping motor. For the dose equivalent at 1cm depth (H1), 3mm (H3) and 70 &mgr;m (H70), the GD-403 showed sufficient linearities against the photon fluences in the energy regions of 8 to 20 keV, 13 to 20 keV and 13 to 20 keV, respectively. However, H3 and H70 did not provide sufficient linearities in the energy region of 8 to 12 keV. Moreover, we compared the result in this experiment with the value calculated from the absorbed dose of air using the mass absorption coefficient for the X-ray energy ranging from 10 to 20 keV.

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