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FEMS Microbiol Lett ; 196(2): 195-9, 2001 Mar 15.
Article in English | MEDLINE | ID: mdl-11267779

ABSTRACT

Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, a chronic enteritis in ruminants. A gene homologous to that of 35-kDa antigen of Mycobacterium leprae was cloned and sequenced from Mycobacterium paratuberculosis. The database searches revealed 82.79% and 95.67% similarities of its nucleotide sequence, with those of immunodominant 35-kDa protein of M. leprae and M. avium, respectively.


Subject(s)
Antigens, Bacterial/genetics , Bacterial Proteins/genetics , Mycobacterium avium subsp. paratuberculosis/genetics , Amino Acid Sequence , Animals , Antigens, Bacterial/analysis , Bacterial Proteins/analysis , Cattle , Cloning, Molecular , Conserved Sequence , Genes, Bacterial , Molecular Sequence Data , Mycobacterium avium subsp. paratuberculosis/classification , Oligonucleotide Probes , Open Reading Frames , Polymerase Chain Reaction , Sequence Homology, Amino Acid
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