Empowering Precision Medicine: Unlocking Revolutionary Insights through Blockchain-Enabled Federated Learning and Electronic Medical Records.

Precision medicine has emerged as a transformative approach to healthcare, aiming to deliver personalized treatments and therapies tailored to individual patients. However, the realization of precision medicine relies heavily on the availability of comprehensive and diverse medical data. In this context, blockchain-enabled federated learning, coupled with electronic medical records (EMRs), presents a groundbreaking solution to unlock revolutionary insights in precision medicine. This abstract explores the potential of blockchain technology to empower precision medicine by enabling secure and decentralized data sharing and analysis. By leveraging blockchain's immutability, transparency, and cryptographic protocols, federated learning can be conducted on distributed EMR datasets without compromising patient privacy. The integration of blockchain technology ensures data integrity, traceability, and consent management, thereby addressing critical concerns associated with data privacy and security. Through the federated learning paradigm, healthcare institutions and research organizations can collaboratively train machine learning models on locally stored EMR data, without the need for data centralization. The blockchain acts as a decentralized ledger, securely recording the training process and aggregating model updates while preserving data privacy at its source. This approach allows the discovery of patterns, correlations, and novel insights across a wide range of medical conditions and patient populations. By unlocking revolutionary insights through blockchain-enabled federated learning and EMRs, precision medicine can revolutionize healthcare delivery. This paradigm shift has the potential to improve diagnosis accuracy, optimize treatment plans, identify subpopulations for clinical trials, and expedite the development of novel therapies. Furthermore, the transparent and auditable nature of blockchain technology enhances trust among stakeholders, enabling greater collaboration, data sharing, and collective intelligence in the pursuit of advancing precision medicine. In conclusion, this abstract highlights the transformative potential of blockchain-enabled federated learning in empowering precision medicine. By unlocking revolutionary insights from diverse and distributed EMR datasets, this approach paves the way for a future where healthcare is personalized, efficient, and tailored to the unique needs of each patient.

Securing Secrets in Cyber-Physical Systems: A Cutting-Edge Privacy Approach with Consortium Blockchain.

In the era of interconnected and intelligent cyber-physical systems, preserving privacy has become a paramount concern. This paper aims a groundbreaking proof-of-concept (PoC) design that leverages consortium blockchain technology to address privacy challenges in cyber-physical systems (CPSs). The proposed design introduces a novel approach to safeguarding sensitive information and ensuring data integrity while maintaining a high level of trust among stakeholders. By harnessing the power of consortium blockchain, the design establishes a decentralized and tamper-resistant framework for privacy preservation. However, ensuring the security and privacy of sensitive information within CPSs poses significant challenges. This paper proposes a cutting-edge privacy approach that leverages consortium blockchain technology to secure secrets in CPSs. Consortium blockchain, with its permissioned nature, provides a trusted framework for governing the network and validating transactions. By employing consortium blockchain, secrets in CPSs can be securely stored, shared, and accessed by authorized entities only, mitigating the risks of unauthorized access and data breaches. The proposed approach offers enhanced security, privacy preservation, increased trust and accountability, as well as interoperability and scalability. This paper aims to address the limitations of traditional security mechanisms in CPSs and harness the potential of consortium blockchain to revolutionize the management of secrets, contributing to the advancement of CPS security and privacy. The effectiveness of the design is demonstrated through extensive simulations and performance evaluations. The results indicate that the proposed approach offers significant advancements in privacy protection, paving the way for secure and trustworthy cyber-physical systems in various domains.

HealthLock: Blockchain-Based Privacy Preservation Using Homomorphic Encryption in Internet of Things Healthcare Applications.

The swift advancement of the Internet of Things (IoT), coupled with the growing application of healthcare software in this area, has given rise to significant worries about the protection and confidentiality of critical health data. To address these challenges, blockchain technology has emerged as a promising solution, providing decentralized and immutable data storage and transparent transaction records. However, traditional blockchain systems still face limitations in terms of preserving data privacy. This paper proposes a novel approach to enhancing privacy preservation in IoT-based healthcare applications using homomorphic encryption techniques combined with blockchain technology. Homomorphic encryption facilitates the performance of calculations on encrypted data without requiring decryption, thus safeguarding the data's privacy throughout the computational process. The encrypted data can be processed and analyzed by authorized parties without revealing the actual contents, thereby protecting patient privacy. Furthermore, our approach incorporates smart contracts within the blockchain network to enforce access control and to define data-sharing policies. These smart contracts provide fine-grained permission settings, which ensure that only authorized entities can access and utilize the encrypted data. These settings protect the data from being viewed by unauthorized parties. In addition, our system generates an audit record of all data transactions, which improves both accountability and transparency. We have provided a comparative evaluation with the standard models, taking into account factors such as communication expense, transaction volume, and security. The findings of our experiments suggest that our strategy protects the confidentiality of the data while at the same time enabling effective data processing and analysis. In conclusion, the combination of homomorphic encryption and blockchain technology presents a solution that is both resilient and protective of users' privacy for healthcare applications integrated with IoT. This strategy offers a safe and open setting for the management and exchange of sensitive patient medical data, while simultaneously preserving the confidentiality of the patients involved.

An Adaptive Early Stopping Technique for DenseNet169-Based Knee Osteoarthritis Detection Model.

Knee osteoarthritis (OA) detection is an important area of research in health informatics that aims to improve the accuracy of diagnosing this debilitating condition. In this paper, we investigate the ability of DenseNet169, a deep convolutional neural network architecture, for knee osteoarthritis detection using X-ray images. We focus on the use of the DenseNet169 architecture and propose an adaptive early stopping technique that utilizes gradual cross-entropy loss estimation. The proposed approach allows for the efficient selection of the optimal number of training epochs, thus preventing overfitting. To achieve the goal of this study, the adaptive early stopping mechanism that observes the validation accuracy as a threshold was designed. Then, the gradual cross-entropy (GCE) loss estimation technique was developed and integrated to the epoch training mechanism. Both adaptive early stopping and GCE were incorporated into the DenseNet169 for the OA detection model. The performance of the model was measured using several metrics including accuracy, precision, and recall. The obtained results were compared with those obtained from the existing works. The comparison shows that the proposed model outperformed the existing solutions in terms of accuracy, precision, recall, and loss performance, which indicates that the adaptive early stopping coupled with GCE improved the ability of DenseNet169 to accurately detect knee OA.

COVID-19 Pandemic and Its Effect on Resident Physicians' Mental Well-Being: A Cross-Sectional Study in Kuwait.

OBJECTIVE: Concerns about COVID-19's long-term consequences on the mental health of frontline health professionals are mounting as the entire world strives anew to contain it. The primary objective of this research is to describe the impact of working during the COVID-19 pandemic on resident physicians' mental health. SUBJECT AND METHODS: A cross-sectional online survey using the Google Forms platform was conducted from May 1 to May 30, 2021, on 311 residents currently enrolled in a residency program at the Kuwait Institutional of Medical Specialization (KIMS). Socio-demographic details of each resident physician were collected and the scores related to depression, anxiety, and stress were measured using the previously validated depression anxiety stress scale-21 (DASS-21). RESULTS: Higher stress and depression scores were seen in those who were devoid of the option to work with COVID-19 patients, who reported that working during the pandemic affected their study schedule, and who lost off-service training time. Further, the anxiety scores were significantly higher in females. CONCLUSION: The impact of the ongoing pandemic on residents' mental health is grave, necessitating psychological treatment and support. The study discovered various factors linked to depression, anxiety, and stress. As a result, these aspects must be regarded to protect the doctors' mental health.

Deep Ensemble Fake News Detection Model Using Sequential Deep Learning Technique.

Recently, fake news has been widely spread through the Internet due to the increased use of social media for communication. Fake news has become a significant concern due to its harmful impact on individual attitudes and the community's behavior. Researchers and social media service providers have commonly utilized artificial intelligence techniques in the recent few years to rein in fake news propagation. However, fake news detection is challenging due to the use of political language and the high linguistic similarities between real and fake news. In addition, most news sentences are short, therefore finding valuable representative features that machine learning classifiers can use to distinguish between fake and authentic news is difficult because both false and legitimate news have comparable language traits. Existing fake news solutions suffer from low detection performance due to improper representation and model design. This study aims at improving the detection accuracy by proposing a deep ensemble fake news detection model using the sequential deep learning technique. The proposed model was constructed in three phases. In the first phase, features were extracted from news contents, preprocessed using natural language processing techniques, enriched using n-gram, and represented using the term frequency-inverse term frequency technique. In the second phase, an ensemble model based on deep learning was constructed as follows. Multiple binary classifiers were trained using sequential deep learning networks to extract the representative hidden features that could accurately classify news types. In the third phase, a multi-class classifier was constructed based on multilayer perceptron (MLP) and trained using the features extracted from the aggregated outputs of the deep learning-based binary classifiers for final classification. The two popular and well-known datasets (LIAR and ISOT) were used with different classifiers to benchmark the proposed model. Compared with the state-of-the-art models, which use deep contextualized representation with convolutional neural network (CNN), the proposed model shows significant improvements (2.41%) in the overall performance in terms of the F1score for the LIAR dataset, which is more challenging than other datasets. Meanwhile, the proposed model achieves 100% accuracy with ISOT. The study demonstrates that traditional features extracted from news content with proper model design outperform the existing models that were constructed based on text embedding techniques.

A Fuzzy-Based Context-Aware Misbehavior Detecting Scheme for Detecting Rogue Nodes in Vehicular Ad Hoc Network.

A vehicular ad hoc network (VANET) is an emerging technology that improves road safety, traffic efficiency, and passenger comfort. VANETs' applications rely on co-operativeness among vehicles by periodically sharing their context information, such as position speed and acceleration, among others, at a high rate due to high vehicles mobility. However, rogue nodes, which exploit the co-operativeness feature and share false messages, can disrupt the fundamental operations of any potential application and cause the loss of people's lives and properties. Unfortunately, most of the current solutions cannot effectively detect rogue nodes due to the continuous context change and the inconsideration of dynamic data uncertainty during the identification. Although there are few context-aware solutions proposed for VANET, most of these solutions are data-centric. A vehicle is considered malicious if it shares false or inaccurate messages. Such a rule is fuzzy and not consistently accurate due to the dynamic uncertainty of the vehicular context, which leads to a poor detection rate. To this end, this study proposed a fuzzy-based context-aware detection model to improve the overall detection performance. A fuzzy inference system is constructed to evaluate the vehicles based on their generated information. The output of the proposed fuzzy inference system is used to build a dynamic context reference based on the proposed fuzzy inference system. Vehicles are classified into either honest or rogue nodes based on the deviation of their evaluation scores calculated using the proposed fuzzy inference system from the context reference. Extensive experiments were carried out to evaluate the proposed model. Results show that the proposed model outperforms the state-of-the-art models. It achieves a 7.88% improvement in the overall performance, while a 16.46% improvement is attained for detection rate compared to the state-of-the-art model. The proposed model can be used to evict the rogue nodes, and thus improve the safety and traffic efficiency of crewed or uncrewed vehicles designed for different environments, land, naval, or air.

A Novel Feature-Engineered-NGBoost Machine-Learning Framework for Fraud Detection in Electric Power Consumption Data.

This study presents a novel feature-engineered-natural gradient descent ensemble-boosting (NGBoost) machine-learning framework for detecting fraud in power consumption data. The proposed framework was sequentially executed in three stages: data pre-processing, feature engineering, and model evaluation. It utilized the random forest algorithm-based imputation technique initially to impute the missing data entries in the acquired smart meter dataset. In the second phase, the majority weighted minority oversampling technique (MWMOTE) algorithm was used to avoid an unequal distribution of data samples among different classes. The time-series feature-extraction library and whale optimization algorithm were utilized to extract and select the most relevant features from the kWh reading of consumers. Once the most relevant features were acquired, the model training and testing process was initiated by using the NGBoost algorithm to classify the consumers into two distinct categories ("Healthy" and "Theft"). Finally, each input feature's impact (positive or negative) in predicting the target variable was recognized with the tree SHAP additive-explanations algorithm. The proposed framework achieved an accuracy of 93%, recall of 91%, and precision of 95%, which was greater than all the competing models, and thus validated its efficacy and significance in the studied field of research.

Fairness-Oriented Semichaotic Genetic Algorithm-Based Channel Assignment Technique for Node Starvation Problem in Wireless Mesh Networks.

Wireless mesh networks (WMNs) have emerged as a scalable, reliable, and agile wireless network that supports many types of innovative technologies such as the Internet of Things (IoT), Wireless Sensor Networks (WSN), and Internet of Vehicles (IoV). Due to the limited number of orthogonal channels, interference between channels adversely affects the fair distribution of bandwidth among mesh clients, causing node starvation in terms of insufficient bandwidth distribution, which impedes the adoption of WMN as an efficient access technology. Therefore, a fair channel assignment is crucial for the mesh clients to utilize the available resources. However, the node starvation problem due to unfair channel distribution has been vastly overlooked during channel assignment by the extant research. Instead, existing channel assignment algorithms equally distribute the interference reduction on the links to achieve fairness which neither guarantees a fair distribution of the network bandwidth nor eliminates node starvation. In addition, the metaheuristic-based solutions such as genetic algorithm, which is commonly used for WMN, use randomness in creating initial population and selecting the new generation usually leading the search to local minima. To this end, this study proposes a Fairness-Oriented Semichaotic Genetic Algorithm-Based Channel Assignment Technique (FA-SCGA-CAA) to solve node starvation problem in wireless mesh networks. FA-SCGA-CAA maximizes link fairness while minimizing link interference using a genetic algorithm (GA) with a novel nonlinear fairness-oriented fitness function. The primary chromosome with powerful genes is created based on multicriterion links ranking channel assignment algorithm. Such a chromosome was used with a proposed semichaotic technique to create a strong population that directs the search towards the global minima effectively and efficiently. The proposed semichaotic technique was also used during the mutation and parent selection of the new genes. Extensive experiments were conducted to evaluate the proposed algorithm. A comparison with related work shows that the proposed FA-SCGA-CAA reduced the potential node starvation by 22% and improved network capacity utilization by 23%. It can be concluded that the proposed FA-SCGA-CAA is reliable to maintain high node-level fairness while maximizing the utilization of the network resources, which is the ultimate goal of many wireless networks.

Feasibility and safety of day-surgery laparoscopic cholecystectomy: a single-institution 5-year experience of 1140 cases

BACKGROUNDS/AIMS: We report our experience with day-surgery laparoscopic cholecystectomy and assess its feasibility and safety. METHODS: Data was collected on all the patients who underwent day-surgery laparoscopic cholecystectomy between February 2009 and February 2014 at Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. All patients had symptomatic cholelithiasis that was proven on imaging studies with clearance of the common bile duct. The patient biographical data (age, gender, American Society of Anaesthesiology status, medical comorbidities) and surgical outcomes were then obtained. There was an evaluation of the success rate of day-surgery laparoscopic cholecystectomy, reasons for unexpected admission, and the re-admission rate. RESULTS: A total of 1,140 patients were included in this study. The success rate for day-surgery laparoscopic cholecystectomy was 96%. The reasons for unexpected hospital admission for 46 patients (4%) included persistent abdominal pain and postoperative emesis. The postoperative re-admission rate was 0.4% (5 patients). There were no major complications, and the conversion rate was 0.5% (6 patients). CONCLUSIONS: We suggest that day-surgery laparoscopic cholecystectomy is both safe and feasible in a local setting. Careful patient selection is essential in ensuring a high success rate.