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1.
Chem Biodivers ; 9(8): 1403-21, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22899602

ABSTRACT

The plants of genus Cipadessa, which are distributed across India and southwest of China, have been used as natural insecticides, as well as folk medicines for the treatment of a range of maladies such as diabetes, dysentery, malaria, piles, snake poison, rheumatism, etc. This article reviews the chemical constituents that have been isolated from Cipadessa species to date, including their biological activities. The compounds listed are tetranortriterpenoids (limonoids), diterpenoids, sesquiterpenoids, flavonoids, steroids, and some others.


Subject(s)
Flavonoids/chemistry , Flavonoids/pharmacology , Meliaceae/chemistry , Steroids/chemistry , Steroids/pharmacology , Terpenes/chemistry , Terpenes/pharmacology , Animals , Anti-Infective Agents/chemistry , Anti-Infective Agents/metabolism , Anti-Infective Agents/pharmacology , Antineoplastic Agents/chemistry , Antineoplastic Agents/metabolism , Antineoplastic Agents/pharmacology , China , Cytotoxins/chemistry , Cytotoxins/metabolism , Cytotoxins/pharmacology , Flavonoids/metabolism , Humans , India , Insecticides/chemistry , Insecticides/metabolism , Insecticides/pharmacology , Meliaceae/metabolism , Plant Extracts/chemistry , Plant Extracts/metabolism , Plant Extracts/pharmacology , Steroids/metabolism , Terpenes/metabolism
2.
Chem Biodivers ; 9(2): 251-71, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22344903

ABSTRACT

The genus Ochna L. (Gr, Ochne; wild pear), belonging to the Ochnaceae family, includes ca. 85 species of evergreen trees, shrubs, and shrublets, distributed in tropical Asia, Africa, and America. Several members of this genus have long been used in folk medicine for treatment of various ailments, such as asthma, dysentery, epilepsy, gastric disorders, menstrual complaints, lumbago, ulcers, as an abortifacient, and as antidote against snake bites. Up to now, ca. 111 constituents, viz. flavonoids (including bi-, tri-, and pentaflavonoids), anthranoids, triterpenes, steroids, fatty acids, and a few others have been identified in the genus. Crude extracts and isolated compounds have been found to exhibit analgesic, anti-HIV-1, anti-inflammatory, antimalarial, antimicrobial, and cytotoxic activities, lending support to the rationale behind several of its traditional uses. The present review compiles the informations concerning the traditional uses, phytochemistry, and biological activities of Ochna.


Subject(s)
Biological Products/pharmacology , Ochnaceae/chemistry , Phytotherapy , Plant Extracts/pharmacology , Animals , Humans
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