Selection of green carrier solvent for the effective creation of bio-inspired liquid formulation and anti-fungal potency evaluation.

Existing pesticide formulation solvents generate volatile organic compounds (VOCs), are combustible, and are classed as hazardous air pollutants (HAPs), meaning they are detrimental to users and phytotoxic to crops. Green solvents are required in formulations due to regulations, health, and environmental concerns. In emulsifiable concentration (EC) formulations, the "green chemistry" movement has led to the use of less harmful solvents. After a detailed and comparative fungal growth inhibition assessment, the least harmful carrier solvent among four regularly used organic solvents [dimethyl sulfoxide (DMSO), dimethylformamide (DMF), aromatic hydrocarbon (C9), and methyl oleate] was chosen in this study. We employed methyl oleate (cis-9-Octadecenoic acid methyl ester) as a bio-based green reserver (60%) to create effective bioinspired EC formulations (30%) of Pongamia pinnata L extract utilising emulsifier blends (10 percent) based on the known toxicity order (DMF > DMSO > C9 > methyl oleate). EC1 outperformed the other thirteen formulations (EC1-EC13) in terms of emulsion stability, cold test, accelerated storage stability, flash point, and other metrics, proving its suitability for commercial production. Using four therapeutically appropriate concentrations of agricultural usage, in-vitro fungicidal effects against Alternaria solani and Phytophthora spp. were examined.A. solani (EC50 = 0.08 percent) showed the greatest growth suppression (87.4 percent) at the maximum dosage (1 percent), followed by Phytophthora sp. (71.1 percent) (EC50 = 0.49 percent). The study proved its utility in the production of environmentally acceptable green solvent-based herbal formulations as a long-term crop protection alternative to harmful chemical pesticides.

Snowfall Variability Dictates Glacier Mass Balance Variability in Himalaya-Karakoram.

Glaciers in the Himalaya-Karakoram (HK) are critical for ensuring water-security of a large fraction of world's population that is vulnerable to climate impacts. However, the sensitivity of HK glaciers to changes in meteorological forcing remains largely unknown. We analyzed modelled interannual variability of mass balance (MB) that is validated against available observations, to quantify the sensitivity of MB to meteorological factors over the HK. Within the model, snowfall variability (0.06 m/yr) explains ~60% of the MB variability (0.28 m/yr), implying a sensitivity of MB on snowfall to the tune of several hundreds of percent. This stunningly high sensitivity of MB to snowfall offers crucial insights into the mechanism of the recent divergent glacier response over the HK. Our findings underscore the need for sustained measurements and model representations of the spatiotemporal variability of snowfall, one of the least-studied factors over the glacierized HK, for capturing the large-scale and yet region-specific glacier changes taking place over the HK.

Unusual liquid state of hard-core bosons on the pyrochlore lattice.

We study the physics of hard-core bosons with unfrustrated hopping (t) and nearest-neighbor repulsion (V) on the three dimensional pyrochlore lattice. At half-filling, we demonstrate that the small V/t superfluid state eventually becomes unstable at large enough V/t to an unusual insulating state which displays no broken lattice translation symmetry. Equal time and static density correlators in this insulator are well described by a mapping to electric field correlators in the Coulomb phase of a U(1) lattice gauge theory, allowing us to identify this insulator with a U(1) fractionalized Mott-insulating state. The possibility of observing this phase in suitably designed atom-trap experiments with ultracold atoms is also discussed, as are specific experimental signatures.