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Pract Neurol ; 9(4): 221-4, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19608771

ABSTRACT

A 44-year-old man is described with severe flaccid quadriparesis that evolved over 3 weeks. He had regularly binged on alcohol-up to 20 cans of beer per day with occasional consumption of spirits-for more than 15 years but had balanced this with regular food intake. However, for a week prior to the current episode he had not eaten anything of significance. Nerve conduction studies revealed a background peripheral, mainly sensory, neuropathy with a superimposed acute motor axonopathy. CSF was normal. He improved with high dose vitamin replacement and physiotherapy but remains dependent on a Zimmer frame for mobility and a splint for wrist drop.


Subject(s)
Alcohol-Induced Disorders, Nervous System/diagnosis , Beriberi/diagnosis , Guillain-Barre Syndrome/diagnosis , Nutrition Disorders/diagnosis , Quadriplegia/etiology , Adult , Alcohol-Induced Disorders, Nervous System/physiopathology , Alcoholic Neuropathy/diagnosis , Alcoholic Neuropathy/physiopathology , Beriberi/physiopathology , Demyelinating Diseases/chemically induced , Demyelinating Diseases/pathology , Demyelinating Diseases/physiopathology , Diagnosis, Differential , Dietary Supplements , Disease Progression , Foot Deformities/etiology , Guillain-Barre Syndrome/physiopathology , Horner Syndrome/etiology , Horner Syndrome/physiopathology , Humans , Magnetic Resonance Imaging , Male , Motor Neuron Disease/chemically induced , Motor Neuron Disease/diagnosis , Motor Neuron Disease/physiopathology , Muscle Weakness/etiology , Muscle Weakness/physiopathology , Nutrition Disorders/etiology , Nutrition Disorders/physiopathology , Pons/pathology , Quadriplegia/physiopathology , Thiamine Deficiency/diagnosis , Thiamine Deficiency/physiopathology , Treatment Outcome
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