[Effects of long term hypercapnia on plasma amino acids in the rat (author's transl)]. / Effets de l'hypercapnie prolongée sur les acides aminés du plasma chez le rat

Rats have been placed for periods from two hours to 22 days in a chamber, the atmosphere of which was enriched in CO2 (FICO2: 0.10). The acute phase of hypercapnia induces multidirectional changes of many plasma amino acids. Some of these changes lessen or become of an opposite direction during the first days of exposure; most of them disappear when the hypercapnic acidosis is partly compensated. The variety of these reactions seems due to the fact that CO2 brings into play various mechanisms of synthesis, circulation and catabolism.