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1.
Pan Afr Med J ; 33: 138, 2019.
Article in English | MEDLINE | ID: mdl-31558936

ABSTRACT

The chordoma is a benign cartilaginous tumor whose sphenoidale localization is exceptional. This tumor has considerable difficulties of both diagnosis and treatment. We report the observation of a Tunisian adult who presented features of hypopituitarism set wrongly on account of a prolactinoma.


Subject(s)
Chordoma/diagnosis , Hypopituitarism/diagnosis , Prolactinoma/diagnosis , Chordoma/pathology , Diagnosis, Differential , Humans , Hypopituitarism/etiology , Magnetic Resonance Imaging , Male , Middle Aged , Prolactinoma/pathology , Sphenoid Bone/pathology , Tunisia
2.
Tunis Med ; 95(6): 444-445, 2017 Jun.
Article in English | MEDLINE | ID: mdl-29512806

ABSTRACT

BACKGROUND: Lung damage during amyopathic dermatomyositis (ADM) associated with auto antibodies anti MDA-5 is serious. We report a rare observation of a severe ADM associated to anti MDA-5 antibodies complicated with diffuse interstitial lung disease (ILD) rapidly extensive and fatal. OBSERVATION: We report the observation of a Tunisian adult who was admitted for ADM. The anti MDA-5 antibodies were detected. He developed an ILD rapidly extensive to fibrosis. Corticosteroids were unefficient and he deceded of pneumomediastin and refractory respiratory distress. CONCLUSION: This observation illustrates the severity of ADM with anti MDA-5 antibodies. Every clinician should detect any ILD to avoid the progression to fibrosis.


Subject(s)
Autoantibodies , Dermatomyositis/immunology , Interferon-Induced Helicase, IFIH1/immunology , Lung Diseases, Interstitial/immunology , Dermatomyositis/complications , Humans , Male , Middle Aged , Severity of Illness Index
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