Subject(s)
Anti-Bacterial Agents/pharmacology , Disease Transmission, Infectious/prevention & control , Primary Prevention/methods , Salmonella typhi , Typhoid Fever , Disease Management , Drug Resistance, Microbial , Hematologic Tests/methods , Humans , India/epidemiology , Practice Guidelines as Topic , Prevalence , Salmonella typhi/drug effects , Salmonella typhi/isolation & purification , Secondary Prevention/methods , Serologic Tests/methods , Typhoid Fever/diagnosis , Typhoid Fever/epidemiology , Typhoid Fever/physiopathology , Typhoid Fever/therapyABSTRACT
AIMS: To study the profile of irritable bowel syndrome (IBS), and the frequency of such symptoms among the general population, in India. METHODS: In this prospective, multi-center study, data were obtained from 2785 patients with chronic lower gastrointestinal symptoms (complainants) with no alarm feature and negative investigations for organic causes visiting physicians at 30 centers, and from 4500 community subjects (non-complainants), using separate questionnaires. RESULTS: Most complainants were middle-aged (mean age 39.4 years) and male (1891; 68%). The common symptoms were: abdominal pain or discomfort (1958; 70%), abdominal fullness (1951; 70%); subjective feeling of constipation (1404 of 2656; 53%), or diarrhea (1252 of 2656, 47%), incomplete evacuation (2134; 77%), mucus with stools (1506; 54%), straining at stools (1271; 46%), epigastric pain (1364; 49%) and milk intolerance (906; 32%). Median stool frequency was similar in patients who felt they had constipation or those who felt they had diarrhea. Information to subtype symptoms using standard criteria was available in 1301 patients; of these, 507 (39%) had constipation-predominant IBS ( 3
Subject(s)
Irritable Bowel Syndrome/epidemiology , Adult , Female , Gastroenterology , Humans , India/epidemiology , Irritable Bowel Syndrome/physiopathology , Male , Prospective Studies , Societies, MedicalABSTRACT
The diagnosis of Coeliac Disease (CD) till now was done based on histological findings and response to gluten- free diet. Recently, Serological tests like IgA anti-endomysial antibodies (AEA) IgA tissue-transglutamin (tTG), IgA antigliadin antibodies (AGA) and IgG AGA antibodies have been added to the armamentarium. Being a small bowel disorder the upper GI endoscopy and colonoscopy are not of much help. The advent of Capsule Endoscopy (CE) which scans the entire small bowel and gives highly magnified and detailed view of mucosa has facilitated the diagnosis of CD to great extent. Moreover, CE is painless, well tolerated and safe diagnostic procedure. This article presents new frontiers in diagnosis, role of capsule endoscopy, and the first case of diagnosis of CD by CE in India.
Subject(s)
Capsule Endoscopy , Celiac Disease/diagnosis , Immunoglobulin A/immunology , Celiac Disease/immunology , Celiac Disease/pathology , Humans , Male , Middle AgedABSTRACT
Presented here are case reports of two patients who became completely blind in both eyes following acute systemic hypotension - in one following bouts of vomiting and in the other after repeated gastrointestinal bleeding. Both patients had severe degree of anemia. There were no other risk factors for vascular disease such as arteriosclerosis or vasculitis.
Subject(s)
Anemia/complications , Hypotension/complications , Infarction/etiology , Optic Nerve/blood supply , Blindness/etiology , Humans , Male , Middle AgedABSTRACT
A patient who developed syncope due to carotid sinus syndrome is described. The patient was suffering from carcinoma of the pyriform fossa for the past one year and received radiotherapy in the region of the neck for the same. Demand pacing was ineffective in alleviating syncopal episodes. The patient responded to oral administration of an anticholinergic (belladonna) and a sympathomimectic agent (orciprenaline).