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In vitro spasmolytic effect of aqueous extract of Calotropis procera on Guinea-pig trachea smooth muscle chain.
Iwalewa, Ezekiel O; Elujoba, Anthony A; Bankole, Olanrewaju A.
Fitoterapia ; 76(2): 250-3, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15752643

ABSTRACT

The aqueous extract of Calotropis procera was evaluated for its spasmolytic effect using in vitro trachea smooth muscle chain of Guinea-pig. The extract (50, 100 and 200 microg/ml) showed a dose-dependent relaxant activity probably exhibited through the direct relaxant action on the smooth muscle.


Subject(s)
Calotropis , Parasympatholytics/pharmacology , Phytotherapy , Plant Extracts/pharmacology , Trachea/drug effects , Animals , Dose-Response Relationship, Drug , Guinea Pigs , Muscle Contraction/drug effects , Muscle, Smooth/drug effects , Parasympatholytics/administration & dosage , Parasympatholytics/therapeutic use , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use
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