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1.
Einstein (Sao Paulo) ; 21: eAO0197, 2023.
Article in English | MEDLINE | ID: mdl-37585885

ABSTRACT

OBJECTIVE: To analyze the refusal rate of elective aortic aneurysm surgery in asymptomatic patients after the presentation of a detailed informed consent form followed by a meeting where patient and their families can analyze each item. METHODS: We conducted a retrospective analysis of 49 patients who had aneurysms and were offered surgical treatment between June 2017 and February 2019. The patients were divided into two groups: the Rejected Surgery Group, which was composed of patients who refused the proposed surgical treatment, and the Accepted Surgery Group, comprising patients who accepted the proposed surgeries and subsequently underwent them. RESULTS: Of the 49 patients, 13 (26.5%) refused surgery after reading the informed consent and attending the comprehensive meeting. We observed that patients who refused surgery had statistically smaller aneurysms than those who accepted surgery (9% versus 26%). These smaller aneurysms were above the indication size, according to the literature. CONCLUSION: One-quarter of patients who were indicated for elective surgical repair of aortic aneurysms rejected surgery after shared decision-making, which involved presenting patients with an informed consent form followed by a clarification meeting for them and their families to analyze each item. The only factor that significantly influenced a rejection of the procedure was the size of the aneurysm; patients who rejected surgery had smaller aneurysms than those who accepted surgery. Up to 26% of patients with aortic aneurysms refused surgical repair. The proposed technique, whether open or endovascular, did not influence patients' decisions. Patients with smaller aneurysms were more likely to refuse aortic aneurysm treatment.


Subject(s)
Aortic Aneurysm, Abdominal , Aortic Aneurysm , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Humans , Retrospective Studies , Aortic Aneurysm, Abdominal/surgery , Aortic Aneurysm/etiology , Aortic Aneurysm/surgery , Informed Consent , Treatment Outcome , Endovascular Procedures/adverse effects , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/methods , Risk Factors
2.
Einstein (Säo Paulo) ; 21: eAO0197, 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1448190

ABSTRACT

ABSTRACT Objective To analyze the refusal rate of elective aortic aneurysm surgery in asymptomatic patients after the presentation of a detailed informed consent form followed by a meeting where patient and their families can analyze each item. Methods We conducted a retrospective analysis of 49 patients who had aneurysms and were offered surgical treatment between June 2017 and February 2019. The patients were divided into two groups: the Rejected Surgery Group, which was composed of patients who refused the proposed surgical treatment, and the Accepted Surgery Group, comprising patients who accepted the proposed surgeries and subsequently underwent them. Results Of the 49 patients, 13 (26.5%) refused surgery after reading the informed consent and attending the comprehensive meeting. We observed that patients who refused surgery had statistically smaller aneurysms than those who accepted surgery (9% versus 26%). These smaller aneurysms were above the indication size, according to the literature. Conclusion One-quarter of patients who were indicated for elective surgical repair of aortic aneurysms rejected surgery after shared decision-making, which involved presenting patients with an informed consent form followed by a clarification meeting for them and their families to analyze each item. The only factor that significantly influenced a rejection of the procedure was the size of the aneurysm; patients who rejected surgery had smaller aneurysms than those who accepted surgery.

3.
Angiology ; 73(5): 431-437, 2022 05.
Article in English | MEDLINE | ID: mdl-34753344

ABSTRACT

This study aimed to analyze the incidence of complications resulting from the use of an indwelling arterial catheter (IAC). We compared the characteristics of the patients with an IAC who developed complications with those who did not present any complications. The study included 1,869 patients with an IAC hospitalized in intensive care units (ICUs) between 2017 and 2018. Most patients were male (58.7%), in the seventh decade of life, and had systemic arterial hypertension. The most common site of IAC implantation was the radial artery. Fifty-four (2.88%) cases of complications related to an IAC were identified including bleeding, hematomas, and thrombosis. Female patients had a higher risk of complications (P = .030). Comorbidities such as arrhythmias (P < .001) and peripheral arterial disease (P = .041) also increased that risk. The use of vasoactive drugs (P = .001), hemodialysis (P = .001), and orotracheal intubation (OTI) (P = .001) was significantly associated with the occurrence of complications as well as length of stay in ICUs (P < .001) and IAC duration (P = .001). IACs are safe devices commonly used in ICUs, with an incidence of complications of 2.88%.


Subject(s)
Catheterization, Peripheral , Catheters, Indwelling , Blood Pressure , Catheterization, Peripheral/adverse effects , Catheters, Indwelling/adverse effects , Female , Humans , Intensive Care Units , Male , Radial Artery , Retrospective Studies
4.
World J Hepatol ; 12(7): 399-405, 2020 Jul 27.
Article in English | MEDLINE | ID: mdl-32821338

ABSTRACT

BACKGROUND: Percutaneous transluminal angioplasty and stenting represent an effective treatment for hepatic artery stenosis after liver transplantation. In the first year after stenting, approximately 22% of patients experience in-stent restenosis, increasing the risk of artery thrombosis and related complications, and 50% experience liver failure. Although angiography is an important tool for diagnosis and the planning of therapeutic interventions, it may raise doubts, especially in small-diameter arteries, and it provides low resolution rates compared with newer intravascular imaging methods, such as optical coherence tomography (OCT). CASE SUMMARY: A 64-year-old male developed hepatic artery stenosis one year after orthotropic liver transplantation and was successfully treated with percutaneous transluminal angioplasty with stenting. Five months later, the Doppler ultrasound results indicated restenosis. Visceral arteriography confirmed hepatic artery tortuosity but was doubtful for significant in-stent restenosis (ISR) and intrahepatic flow reduction. To confirm ISR, identify the etiology and guide treatment, OCT was performed. OCT showed severe stenosis due to four mechanisms: Focal and partial stent fracture, late stent malapposition, in-stent neointimal hyperplasia, and neoatherosclerosis. CONCLUSION: Intravascular diagnostic methods can be useful in evaluating cases in which initial angiography results are not sufficient to provide a proper diagnosis of significant stenosis, especially with regard to ISR. A wide range of diagnoses are provided by OCT, resulting in different treatment options. Interventional radiologists should consider intravascular diagnostic methods as additional tools for evaluating patients when visceral angiography results are unclear.

5.
Ann Vasc Surg ; 61: 165-169, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31336159

ABSTRACT

BACKGROUND: The aim of this study is to analyze whether heparin, used as a lock in fully implantable catheter for chemotherapy (portocath), maintains its activity even if it remains in the catheter for a long period of time. METHODS: According to the institutional protocol, all catheters routinely use the lock solution with 3 mL of heparinized solution after chemotherapy and the time interval between each change as lock in the catheters studied ranged from 7 to 30 days. A total of 25 blood samples from 22 patients with 6 types of neoplasia on chemotherapy or not were collected according to routine, and the 10 mL of liquid contained in the first aspirated reservoir/catheter (corresponding to the lock of the last section), were sent for laboratory analysis for prospectively studied with the following tests: anti-Xa, partially activated thromboplastin time (APTT), thrombin time (TT), reptilase, and thromboelastogram. RESULTS: Heparin activity was found in 96% of the anti-Xa and APTT tests. In relation to TT, 92% presented activity. The reptilase test was performed on 24 samples with significant time reduction in all of them. In the INTEM stage, the thromboelastometry test showed activity in 92% of samples and in the HEPTEM phase there was reduction in time in all samples. In all samples, the heparin activity was found to be independent of the time of use. CONCLUSIONS: We can conclude that lock of heparinized solution used in our service in fully implantable central venous catheters for chemotherapy was maintained with active heparin even after a long period of time (up to 30 days), demonstrating that the half-life of the substance within the catheter is greater than its plasma half-life.


Subject(s)
Anticoagulants/administration & dosage , Antineoplastic Agents/administration & dosage , Catheter Obstruction/etiology , Catheterization, Central Venous/instrumentation , Catheters, Indwelling , Central Venous Catheters , Heparin/administration & dosage , Neoplasms/drug therapy , Adult , Aged , Anticoagulants/adverse effects , Anticoagulants/pharmacokinetics , Blood Coagulation Tests , Catheterization, Central Venous/adverse effects , Drug Monitoring/methods , Female , Half-Life , Heparin/adverse effects , Heparin/pharmacokinetics , Humans , Male , Middle Aged , Risk Factors , Time Factors , Treatment Outcome
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