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1.
Physiol Meas ; 44(9)2023 09 26.
Article in English | MEDLINE | ID: mdl-37607562

ABSTRACT

Objective. To explore noise characteristics and the effect physiological activity has on the link between impedance and noise.Approach. Dry-printed electrodes are emerging as a new and exciting technology for skin electro-physiology. Such electrode arrays offer many advantages including user convenience, quick placement, and high resolution. Here we analyze extensive electro-physiological data recorded from the arm and the face to study and quantify the noise of dry electrodes, and to characterize the link between noise and impedance. In particular, we studied the effect of the physiological state of the subject (e.g. rapid eye movement sleep) on noise.Main results. We show that baseline noise values extracted from dry electrodes in the arm are in agreement with the Nyquist equation. In the face, on the other hand, the measured noise values were higher than the values predicted by the Nyquist equation. In addition, we studied how different electrode properties affect performances, including electrode size, shape, and material properties.Significance. Altogether, the results presented here provide a basis for understanding dry electrode performances and substantiate their great potential in electro-physiological investigations.


Subject(s)
Skin Physiological Phenomena , Electric Impedance , Electrodes
2.
Front Neurosci ; 17: 1288069, 2023.
Article in English | MEDLINE | ID: mdl-38264499

ABSTRACT

Introduction: Electrophysiological investigations of intact neural circuits are challenged by the gentle and complex nature of neural tissues. Bi-directional electrophysiological interfacing with the retina, in its intact form, is particularly demanding and currently there is no feasible approach to achieve such investigations. Here we present a feasibility study of a novel soft multi-electrode array suitable for bi-directional electrophysiological study of the intact retina. Methods: Screen-printed soft electrode arrays were developed and tested. The soft probes were designed to accommodate the curvature of the retina in the eye and offer an opportunity to study the retina in its intact form. Results: For the first time, we show both electrical recording and stimulation capabilities from the intact retina. In particular, we demonstrate the ability to characterize retina responses to electrical stimulation and reveal stable, direct, and indirect responses compared with ex-vivo conditions. Discussion: These results demonstrate the unique performances of the new probe while also suggesting that intact retinas retain better stability and robustness than ex-vivo retinas making them more suitable for characterizing retina responses to electrical stimulation.

3.
Phys Rev E ; 105(2-2): 025005, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35291140

ABSTRACT

The linear (Winkler) foundation is a simple model widely used for decades to account for the surface response of elastic bodies. It models the response as purely local, linear, and perpendicular to the surface. We extend this model to the case in which the foundation is made of a structured material such as a polymer network, which has characteristic scales of length and time. We use the two-fluid model of viscoelastic structured materials to treat a film of finite thickness, supported on a rigid solid and subjected to a concentrated normal force at its free surface. We obtain the foundation modulus (Winkler constant) as a function of the film's thickness, intrinsic correlation length, and viscoelastic moduli, for three choices of boundary conditions. The results can be used to readily extend earlier applications of the Winkler model to more complex, microstructured substrates. They also provide a way to extract the intrinsic properties of such complex materials from mechanical surface measurements.

4.
Langmuir ; 36(14): 3981-3987, 2020 Apr 14.
Article in English | MEDLINE | ID: mdl-32207950

ABSTRACT

We study theoretically the surface response of a semi-infinite viscoelastic polymer network using the two-fluid model. We focus on the overdamped limit and on the effect of the network's intrinsic length scales. We calculate the decay rate of slow surface fluctuations, and the surface displacement in response to a localized force. Deviations from the large-scale continuum response are found at length scales much larger than the network's mesh size. We discuss implications for surface scattering and microrheology. We provide closed-form expressions that can be used for surface microrheology: the extraction of viscoelastic moduli and intrinsic length scales from the motions of tracer particles lying on the surface without doping the bulk material.

5.
Phys Rev E ; 96(2-1): 022607, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28950521

ABSTRACT

We study theoretically the velocity cross-correlations of a viscous fluid confined in a slit between two viscoelastic media. We analyze the effect of these correlations on the motions of particles suspended in the fluid. The compliance of the confining boundaries gives rise to a long-ranged pair correlation, decaying only as 1/r with the interparticle distance r. We show how this long-ranged effect may be used to extract the viscoelastic properties of the confining media without embedding tracer particles in them. We discuss the remarkable robustness of such a potential technique with respect to details of the confinement, and its expected statistical advantages over standard two-point microrheology.

6.
Phys Rev E ; 96(3-2): 039902, 2017 Sep.
Article in English | MEDLINE | ID: mdl-29347008

ABSTRACT

This corrects the article DOI: 10.1103/PhysRevE.96.022607.

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