Subject(s)
DNA, Mitochondrial/genetics , Heart Failure/genetics , Point Mutation/genetics , Acute Disease , Autoradiography/methods , Echocardiography/methods , Heart Failure/diagnosis , Humans , Hypertrophy, Left Ventricular/diagnosis , Hypertrophy, Left Ventricular/genetics , Male , Middle Aged , Mitochondrial Diseases/genetics , Multimodal Imaging/methods , Tomography, Optical Coherence/methods , Ventricular Dysfunction, Left/diagnosis , Ventricular Dysfunction, Left/geneticsABSTRACT
PURPOSE: To compare contrast acuity at different illumination levels, color vision, and the subjective visual impression in patients after bilateral cataract surgery with mixed implantation of a yellow-tinted intraocular lens (IOL) and an orange-tinted IOL. SETTING: Department of Ophthalmology, Hietzing Hospital, Vienna, Austria. DESIGN: Prospective case series. METHODS: Consecutive patients with age-related cataract had standardized small-incision cataract surgery with IOL implantation in the capsular bag. Patients were randomly assigned to receive a yellow Polylens Y30 in 1 eye and an Orange Series model PC 440Y in the contralateral eye. The main outcome measures were contrast acuity, color vision, and subjective visual impression. Contrast acuity was measured at illumination levels of 5.0 lux and 0.5 lux and contrast levels of 50.0%, 25.0%, and 12.5%. Color vision was assessed using the Heidelberg-multicolor anomaloscope, and the subjective visual impression was evaluated using a questionnaire. RESULTS: This study included 64 eyes of 32 patients. The intraindividual comparison showed no significant difference in contrast sensitivity at different contrast and illumination levels or in color vision. On questioning, 3 patients reported a difference in subjective color perception between the 2 IOL types. CONCLUSION: There were no differences in contrast sensitivity or color vision between yellow-tinted IOLs and orange-tinted IOLs. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
Subject(s)
Color Perception/physiology , Contrast Sensitivity/physiology , Filtration , Lens Implantation, Intraocular , Lenses, Intraocular , Light , Phacoemulsification , Aged , Aged, 80 and over , Color Vision/physiology , Double-Blind Method , Female , Humans , Male , Middle Aged , Prospective Studies , Prosthesis Design , Surveys and Questionnaires , Visual Acuity/physiologyABSTRACT
BACKGROUND: To compare the intensity of posterior capsule opacification (PCO) between two intraocular lenses (IOLs) of the same optic material, but with different haptic design (1-piece vs. 3-piece). METHODS: This prospective intraindividual controlled cohort study comprised eighty eyes of 40 patients with bilateral age-related cataract. Each patient received a Polylens Y10 (Polytech, Germany) 1-piece IOL in 1 eye and a Polylens Y30 (Polytech, Germany) 3-piece IOL in the contralateral eye. The IOL type in the first operated eye was randomly assigned before patient recruitment. Digital slitlamp photographs were taken 1 year postoperatively using a standardized photographic technique for regeneratory PCO. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software. RESULTS: The Polylens Y10 (1-piece) group showed significantly higher regeneratory and fibrotic PCO scores 1 year after surgery in subjective slitlamp evaluation, however not with objective evaluation using automated image-analysis software. Subjective PCO assessment resulted in a mean PCO score (scale = 0-10) of 1.6 in the Polylens Y10 group and 0.6 in the Polylens Y30 group at 1 year (p < 0.05). The mean automated image-analysis software PCO score was 1.5 in the Polylens Y10 group and 0.9 in the Polylens Y30 group (p = 0.6). CONCLUSION: Both investigated IOLs showed good clinical performance regarding PCO, BCVA and IOL-centration. The Polylens Y10 IOL showed slightly more regeneratory PCO than the 3-piece acrylic IOL 1 year after surgery.
