ABSTRACT
Nasal tip support is an important factor to be considered in rhinoplasty surgery. There are several techniques for improving tip support. Caudal extension graft (CEG) and columellar strut with plumping graft (CSPG) are two methods in rhinoplasty surgery. The final goal of this experimental study is to find the most effective method for tip correction among patients with tip ptosis. In this study, we compare two different methods which are used for the tip correction among patients who suffer from acute nasolabial angle (NLA) and columellar retraction. We performed a randomized clinical trial to compare correction ratio of NLA and columellar show obtained via CEG and CSPG methods. Standardized photographs were taken before the surgery and 12 months after the surgery to compare results between two groups. The mean post-operation NLA was 112.55° in CEG and 104.17° in CSPG (p value < 0.001). Correction ratio of NLA was 22.26° in CEG and 13.77° in CSPG (p value < 0.001). The difference in the mean and the correction ratio of NLA were statistically significant in two groups. The mean post-operation columellar show was 3.75 mm in CEG and 3.44 mm in CSPG (p value < 0.083). The correction ratio of columellar show was 1.76 mm in CEG and 1.20 mm in CSPG (p value < 0.007). The difference in the correction ratio of the two groups was statistically significant. Our study reveals that both techniques properly improve NLA and columellar show, however, CEG is a more stable method in patients with tip ptosis.
Subject(s)
Nasal Cartilages , Nasal Septum , Nose Deformities, Acquired , Rhinoplasty/methods , Transplantation, Autologous/methods , Acute Disease , Adult , Female , Humans , Male , Nasal Cartilages/pathology , Nasal Cartilages/transplantation , Nasal Septum/pathology , Nasal Septum/surgery , Nose Deformities, Acquired/diagnosis , Nose Deformities, Acquired/physiopathology , Nose Deformities, Acquired/surgery , Postoperative Period , Transplants , Treatment OutcomeABSTRACT
BACKGROUND: One of the malignant tumors among head and neck cancers is nasopharyngeal carcinoma. Many studies consider human papilloma virus (HPV) as a cause for nasopharyngeal carcinoma. METHODS: 41 paraffin-wax-embedded block samples were examined to detect HPV DNA and its subtype's presence by polymerase chain reaction. The recurrence, prognosis and survival were evaluated for an average of 48 months. RESULTS: HPV DNA was positive in 9 patients (22%). The overall recurrence rate was 75% in HPV negative patients and 11% in HPV positive ones. The mortality rate in HPV negative and positive patients was 37.5% and 0%, respectively. CONCLUSION: HPV type 18 and 16 were the most common subtypes. Also, it can be implied that patients which are HPV positive had better prognosis and also less recurrence.
Subject(s)
Carcinoma, Squamous Cell/mortality , Nasopharyngeal Neoplasms/mortality , Neoplasm Recurrence, Local/mortality , Papillomaviridae/isolation & purification , Papillomavirus Infections/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Carcinoma , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/therapy , Carcinoma, Squamous Cell/virology , Chemoradiotherapy , DNA, Viral/genetics , Female , Follow-Up Studies , Humans , Male , Middle Aged , Nasopharyngeal Carcinoma , Nasopharyngeal Neoplasms/pathology , Nasopharyngeal Neoplasms/therapy , Nasopharyngeal Neoplasms/virology , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/therapy , Neoplasm Recurrence, Local/virology , Neoplasm Staging , Papillomaviridae/genetics , Papillomavirus Infections/pathology , Papillomavirus Infections/therapy , Papillomavirus Infections/virology , Polymerase Chain Reaction , Prognosis , Survival Rate , Young AdultABSTRACT
OBJECTIVE: Tonsillectomy is a common operation performed in children and young adults. Pain and post-operation haemorrhage are its most common complications. This study was designed to evaluate the efficacy of topical antibiotics in reducing throat pain after tonsillectomy in adult patients. METHODS: A double-blind, placebo-controlled, randomised clinical trial was conducted, enrolling 30 patients older than 18 years who were scheduled to undergo tonsillectomy. Patients were randomly assigned to receive either clindamycin or normal saline (as placebo). Throat pain severity was evaluated using a visual analogue scale. RESULTS: All patients in both groups had experienced a reduction in pain by the seventh day after surgery. There was no statistically significant difference in the extent of visual analogue scale pain score reduction, comparing the placebo and clindamycin groups throughout the study course (p = 0.424). CONCLUSION: Topical clindamycin was not demonstrated to be more effective than normal saline in the reduction of throat pain following tonsillectomy in adults.
Subject(s)
Anti-Bacterial Agents/administration & dosage , Clindamycin/administration & dosage , Pain, Postoperative/prevention & control , Tonsillectomy/adverse effects , Tonsillitis/surgery , Administration, Topical , Adolescent , Adult , Double-Blind Method , Humans , Pharyngitis/prevention & control , Secondary Prevention , Treatment Outcome , Young AdultABSTRACT
Hypertrophy of adenoids is usually caused by repeated throat infections, especially viral and bacterial infections, that in microscopic examination reveal reactive lymphoid follicular hyperplasia. Herein, we present an 11-year-old boy who developed hearing loss in his left ear three months before admission, and in direct examination the adenoids were hypertrophied. Histopathological study of the resected adenoid revealed caseating granulomatous inflammation. Based on histopathological and clinical findings, primary tuberculosis of adenoids was suggested which was confirmed by PCR.
