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Am J Kidney Dis ; 12(6): 510-5, 1988 Dec.
Article in English | MEDLINE | ID: mdl-2973747

ABSTRACT

Atrial natriuretic factor (ANF) levels were ten times normal in hemodialysis patients before dialysis. ANF was not cleared by the dialyzer membrane but plasma levels decreased 47% by the end of dialysis. Patients undergoing peritoneal dialysis had plasma ANF levels four times normal and had detectable ANF in their dialysate. Hemodialysis patients with a marked fall in BP after dialysis had higher ANF levels (P less than 0.05) and lower norepinephrine (NE) levels (P less than 0.05) associated with a failure to increase NE in response to dialysis. Elevated ANF levels are associated with postdialysis hypotension in hemodialysis patients.


Subject(s)
Atrial Natriuretic Factor/blood , Hypotension, Orthostatic/blood , Kidney Failure, Chronic/blood , Adult , Aged , Female , Humans , Kidney Failure, Chronic/therapy , Male , Metanephrine/blood , Middle Aged , Norepinephrine/blood , Normetanephrine/blood , Peritoneal Dialysis , Renal Dialysis
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