[A specialized product of therapeutic nutrition is a dry protein composite mixture enriched with calcium of dairy origin, in the postoperative rehabilitation of elderly and senile patients.]

The study of a specialized product of therapeutic nutrition - a mixture of protein composite dry, enriched with calcium of dairy origin, in the program of complex postoperative rehabilitation of elderly patients, as a dietary remedy for the treatment of enteral insufficiency and prevention of its complications - protein-energy deficiency (BEN). 268 patients aged 61-75 years, operated for various gastroduodenal diseases, were examined. A group of patients (184 people, i. e. 68,6%) without signs of BEN was identified. Of these, the study group consisted of 92 patients, the remaining 92 patients - the control group. The patients of the study group throughout the entire inpatient and post-stationary rehabilitation periods with a total duration of 3 months, in addition to the traditional therapeutic and rehabilitation nutrition of surgical patients, a specialized food product of a dry protein-composite mixture (SBCS) enriched with calcium of dairy origin was added daily in the amount of 27 g. 92 patients of the control group received a similar postoperative surgical diet, but not enriched with calcium. Clinical and laboratory studies have shown that in patients in the study group, during dietary treatment with the use of SBCS enriched with calcium of dairy origin, the indicators of protein, vitamin, mineral metabolism significantly and significantly improved, which served as a preventive factor against the development of BEN in 79,1% of patients. There were only 32,6% of such patients in the control group. Conclusion: a specialized product of therapeutic nutrition - a dry protein composite mixture enriched with calcium of dairy origin, should be included in the postoperative rehabilitation of elderly and senile patients.

[European registry Helicobacter pylori (Hp-EuReg): how has clinical practice changed in Russia from 2013 to 2018 years].

The multicenter prospective observational study initiated by the European Helicobacter and Microbiota Study Group (EHMSG) is conducted in 27 countries in Europe. The data from the Russian part of the European registry for the management of Helicobacter pylori infection (European Registry on the management of Helicobacter pylori infection, protocol: "Hp-EuReg") allows us to analyze the real clinical practice of diagnosis and treatment of H. pylori and compare it with international recommendations. MATERIALS AND METHODS: A comparative analysis of the data entered in the register by the Russian research centers "Hp-EuReg", in the period from 2013 to 2018, was conducted. RESULTS AND DISCUSSION: Invasive diagnostic methods prevail for the primary diagnosis of H. pylori [histology - 20.3% (in 2013 year) - 43.9% (in 2018 year), rapid urease test - 31.7% and 47.8% respectively]. The most popular mode of eradication therapy is a 10-day triple therapy (62.8-76.2%), the effectiveness of which does not exceed 79% (per protocol). Invasive tests (histology) are the leading method for control the effectiveness of therapy, however, there is a tendency towards a wider use of non-invasive methods (H. pylori stool antigen - from 17% in 2013 to 29.3% in 2018 and urea breath test from 6.9 to 18.3%, respectively). Serological test to control the effectiveness of eradication is still used from 8.2% (2013) to 6.1% (2018). Eradication therapy was not performed in 28% of patients throughout the entire observation period. CONCLUSION: In Russia, despite approved domestic and international recommendations, deviations in clinical practice persist, both during eradication therapy and in monitoring the effectiveness of eradication therapy.

[Clinical features of inflammatory bowel disease (ulcerative colitis and Crohn's disease) in geriatric practice in Saint Petersburg.]

Objective - to identify the clinical features of inflammatory bowel disease (IBD) in elderly and senile patients in St. Petersburg. A retrospective analysis of medical charts of 208 patients over 60 years old with inflammatory bowel diseases (IBD) was carried out: 60% of them with ulcerative colitis (UC), 40% with Crohn's disease (CD). The control group consisted of 867 patients aged up to 60 years (UC- 524 patients, 60,4%; CD - 343 patients, 29,6%). Concomitant cardiovascular diseases were detected in 87% of patients, broncho-pulmonary - in 25%, diseases of the bones and joints - in 35%, pathology of the kidneys and urinary tract - in 26,5%, and liver - in 44%. Debut and recurrent IBD were often accompanied (33,6%) by a worsening of somatic pathology (versus 8,7% in other age groups of patients). It's took longer to verify diagnosis of IBD in older patients, than in patients of young and middle ages. Patients with distal localization of the pathological process (proctitis and left-sided colitis) prevailed among patients with UC, the inflammatory form of the disease dominated in patients with CD.