JH-2 constitutive model of sandstone for dynamic problems.

This paper demonstrates the application of the Johnson-Holmquist II (JH-2) model with correlated and validated parameters to simulate the behavior of a sandstone. The JH-2 model is used to simulate various tests, including single-element tests, structural quasi-static uniaxial and triaxial compression tests, and the split Hopkinson pressure bar test. Additionally, the model is used to simulate drop-weight impact test using a ball bearing and two loading scenarios involving small-scale blasting and projectile impacts. Quantitative and qualitative comparisons demonstrate that the JH-2 model agrees well with both experimental and analytical results. Limitations of the model are also highlighted, particularly for quasi-static problems, as the model was originally developed for high-strain-rate simulations. Ultimately, this study demonstrates that the JH-2 rock constitutive model can obtain reasonable results for a material other than the material for which the model was originally correlated and validated. This paper provides valuable guidance for modeling and simulating sandstone and other rock materials subjected to dynamic loadings.

Long-term nusinersen treatment across a wide spectrum of spinal muscular atrophy severity: a real-world experience.

BACKGROUND: Spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by a biallelic mutation in the SMN1 gene, resulting in progressive muscle weakness and atrophy. Nusinersen is the first disease-modifying drug for all SMA types. We report on effectiveness and safety data from 120 adults and older children with SMA types 1c-3 treated with nusinersen. METHODS: Patients were evaluated with the Hammersmith Functional Motor Scale Expanded (HFMSE; n = 73) or the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND; n = 47). Additionally, the Revised Upper Limb Module (RULM) and 6-minute walk test (6MWT) were used in a subset of patients. Patients were followed for up to 30 months of nusinersen treatment (mean, SD; 23, 14 months). Subjective treatment outcomes were evaluated with the Patients Global Impression-Improvement (PGI-I) scale used in all patients or caregivers at each follow-up visit. RESULTS: An increase in the mean HFMSE score was noted at month 14 (T14) (3.9 points, p < 0.001) and month 30 (T30) (5.1 points, p < 0.001). The mean RULM score increased by 0.79 points at T14 (p = 0.001) and 1.96 points (p < 0.001) at month 30 (T30). The mean CHOP-INTEND increased by 3.6 points at T14 (p < 0.001) and 5.6 points at month 26 (p < 0.001). The mean 6MWT improved by 16.6 m at T14 and 27 m at T30 vs. baseline. A clinically meaningful improvement in HFMSE (≥ 3 points) was seen in 62% of patients at T14, and in 71% at T30; in CHOP INTEND (≥ 4 points), in 58% of patients at T14 and in 80% at T30; in RULM (≥ 2 points), in 26.6% of patients at T14 and in 43.5% at T30; and in 6MWT (≥ 30-meter increase), in 26% of patients at T14 and in 50% at T30. Improved PGI-I scores were reported for 75% of patients at T14 and 85% at T30; none of the patients reporting worsening at T30. Adverse events were mild and related to lumbar puncture. CONCLUSIONS: In our study, nusinersen led to continuous functional improvement over 30-month follow-up and was well tolerated by adults and older children with a wide spectrum of SMA severity.

Reoperation rate after fusion and non-fusion surgery for degenerative lumbar spine disease.

Introduction: The number of reoperations increases with the growing number of operations performed. Methods: The clinical material included a group of 2194 patients treated surgically due to degenerative disease of the lumbar spine; we selected a total of 332 patients who were reoperated, and the indications for reoperation were analysed. Results: The percentage of patients operated due to adjacent segment disease in the group of patients with stabilization was on average 8.9%. Conclusions: Indications for stabilizing or preservation of the mobility of the operated segment should provide for the nature of the lesions, and anatomical and surgical conditions.

An Analysis of the Risk Factors for Postural Defects among Early School-Aged Children.

A considerable number of problems begin in childhood due to lifestyle changes, which include a transition from a previous period of extensive movement to prolonged hours of staying in a sitting position at school. The aim of this study was to examine the occurrence of back and side view postural defects in the study group of school-aged children and identify risk factors associated with the formation of postural abnormalities in the study group. METHODS: This study was conducted on a group of 141 children aged 7-10, attending the first to third grades at a primary school in Bialystok (northeastern Poland). This study involved measuring the children's height and weight, assessing the children's body posture based on the FITS method (Functional Individual Scoliosis Therapy) by Bialek and M'hango (the authors of this study), and administering a diagnostic survey addressed to parents and guardians of the children (n = 104) using a self-designed questionnaire. RESULTS: Almost all defects were more prevalent in boys, especially in the case of stature triangles (p = 0.0489) and knee alignment in the sagittal plane (p = 0.038). The age of the subjects differentiated the incidence of defects in the scapulae (p = 0.0037) and shoulder (p = 0.0129) alignment, correlating negatively with age. The risk of postural defects for knees (p = 0.0391) and abdominal arching (p = 0.0240) was significant with a higher BMI. The following lifestyle-related factors were significant: the seat for doing homework (stature triangles p = 0.0253), time spent in front of a computer (positioning of the scapulae in relation to each other p = 0.0233; vertical view of the intergluteal cleft p = 0.0324), and snacking between meals (feet p = 0.0003; shoulder positioning p = 0.0013; stature triangles p = 0.0186; positioning of the scapulae in relation to each other p = 0.0404). CONCLUSIONS: The body posture of the examined children was closed with the head pushed forward and drooped, rounded shoulders, hyperlordosis, and pelvic anteversion. Most exhibited various types of abnormalities related to the feet. The recognized risk factors for posture defects are overweight/obesity, the male gender, children who are older, lack of an adjustable work chair, 2 h a day or more spent using the computer, and snacking between meals.

Metal hypersensitivity in hip, knee and spine surgery.

The number of implanted joint prostheses and damaged spinal components is steadily increasing. At the same time, rejection of the implanted material is observed in operated patients, which manifests itself in both skin and general reactions, as well as loosening and earlier wear of implanted prostheses, which was previously referred to as aseptic reactions. However, it has been shown that in a significant proportion of patients, rejection of implanted material may be caused by hypersensitivity to a specific metal. For this reason, patients qualified for implantation of foreign material, mainly nickel, titanium, chromium, molybdenum, and other alloys, should be subjected to allergy tests to detect possible risks in the form of metal sensitivity reactions.

[Is aseptic loosening of joint prostheses aseptic?] / Czy aseptyczne obluzowanie protez stawów jest aseptyczne?

The observed changes in the periarticular space may be caused by both mechanical action and biological reactions. Periprosthetic infections are the most common cause of loosening and destructive changes in the joints, however, the diagnosis of an aseptic reaction is not always fully obvious. Micromovements between the implant and the surrounding bone can cause remodeling of the bone trabeculae and migration of fibroblasts into the voids between the implant surface and the bone. In addition, repetitive stresses can induce fibroblast proliferation. On the other hand, the residues arising from the wear of implanted materials in the joints may play an important role in the process of loosening of prostheses - both aseptic and septic. Direct interactions between the released molecule and the macrophage surface are sufficient to activate osteoclastogenic signaling pathways. You cannot ignore allergic reactions to metals used in prostheses in patients undergoing arthroplasty. Demonstration of hypersensitivity to the components of dentures in some cases requires the use of appropriate material in order not to cause an inflammatory allergic reaction. Emerging treatment strategies using mesenchymal stem cells (MSCs) are aimed at improving the initial implant integration and preventing periprosthetic osteolysis. It should be emphasized, however, that the diagnosis of aseptic loosening in many clinical situations raises doubts, because it is at the root of everyone.

Analysis of mortality between 2019-2020 at the Neuroorthopedic and Traumatic Orthopedic Departments.

The number of deaths from skeletal injuries is still significant, but is declining with advances in emergency medicine. The adopted principles of emergency procedures and the availability of specialist centres enable the treatment to be effective. AIM: The aim of the study was to analyse the deaths of patients with spine and limb injuries who required surgery. MATERIALS AND METHODS: The analysis covered 22 deaths in the years 2019-2020. The assessment took into account: the cause of admission, the condition of the patient and comorbidities, the medical scales which were used to assess the possible risk of complications, the diagnostic correctness and qualification for surgical treatment, the waiting time for surgery and the cause of death and prior course of action. RESULTS: It can be stated that in 2019, the mortality rate was 0.21 (10 deaths out of 4658 hospitalized), in 2020, the mortality rate was 0.31 (12 deaths out of 3852 hospitalized). The mortality rate in the Department of Traumatic Orthopedics was: 0.30 in 2019 (8 deaths out of 2625 hospitalized) and 0.39 in 2020 (8 deaths in 2020 hospitalized). 10 patients with hip fractures (trochanteric and femoral neck) underwent surgery within 2.7 days (from 1 to 4 days). The causes of death within 1-9 days (average 4.86 days) from admission in this group were complex, and associated with the presence of chronic diseases, including: circulatory failure (9), septic shock (1), heart rhythm disturbances (7), renal failure (6), pulmonary congestion (4), hyperkalemia (1), coagulation disorders (1). In patients after spinal injury with quadriplegia, decompression (1), stabilization (1) and disc removal (1) were performed on the day of admission to the hospital. The patients were hospitalized in the ICU, and deaths occurred on days 9, 15 and 187 from admission due to respiratory and circulatory failure and sudden cardiac arrest. Patients after arthroplasty of the knee (1) and hip (2) were operated on day 2 from admission, and deaths occurred on day 4, 22 and 53 due to: sepsis (1), pulmonary embolism (1), respiratory failure in the course of pneumonia (1). CONCLUSIONS: The deceased were admitted in a serious general condition, burdened with numerous concomitant chronic diseases and their age ranged from 66 to 97 years. The surgical treatment was undertaken for life saving reasons but 5 of the deceased did not undergo surgery due to the extreme general condition leading to respiratory and circulatory failure.

[Pro-health cycle lane versus environmental pollution and trauma]. / Prozdrowotne sciezki rowerowe a zanieczyszczenie srodowiska naturalnego i urazowosc.

A bicycle as a mean of transport and recreation, but is it a healthy lifestyle? The construction of numerous cycle lanes in cities and promotion of physical activity aims to encourage the public to move around by bicycle. The aim of mass cycling is to reduce car exhaust emissions and, on the other hand, to improve public health. The paper presents the potential benefits of cycling, but also its negative effects on the human body. Minimizing the danger of using a bicycle lies not only with cyclists, but also with people who are planning to build cycle lane.

[Pathogenesis and the contemporary picture of polyneuropathy]. / Patogeneza i wspólczesny obraz polineuropatii.

Demyelinating changes in peripheral nerves are responsible for the neurological symptoms found. Diabetes mellitus is one of the most common causes of polyneuropathy and is found in 8-54% of patients with type I diabetes, 13-46% of patients with type II and 22-66% of alcohol abusers. In turn, chemotherapy, depending on the therapeutic regimens used, is responsible for the symptoms of polyneuropathy in 10-90% of patients. Separate disease syndromes create immunologically determined polyneuropathies. Chronic compression or irritation of the spinal nerves or their roots in diseases of the spine leads to ischemia and neuropathy. The spinal nerve is most often pinched and then there are mixed motor-sensory symptoms. In order to prevent the onset of polyneuropathy, it is necessary to release the nerves from pressure and ischemia as quickly as possible.

Numerical Simulation of Vehicle-Lighting Pole Crash Tests: Parametric Study of Factors Influencing Predicted Occupant Safety Levels.

In this paper, numerical simulations of the EN 12767 test procedure for a vehicle-lighting pole crash are presented. A representative soil-vehicle-lighting pole model is first developed. The Geo Metro vehicle model is used, and significant attention is given to representing the soil and its interaction with the traffic pole. Soil is represented using smoothed particle hydrodynamics (SPH) coupled with finite elements (FEs). A parametric study is carried out to investigate the key factors influencing the outcomes and consequently the estimation of the occupant safety levels during crash scenario described in EN 12767. First, a sensitivity study of lighting pole mesh is conducted As a result, the optimal mesh size is used for further studies regarding physical parameters such as soil properties and friction coefficient in vehicle-pole interfaces. Friction and mesh size are found to have a considerable influence on the acceleration severity index (ASI), theoretical head impact velocity (THIV), post-impact velocity and vehicle behavior during the lighting pole crash scenario.

Hip arthoplasty in a forester after numerous tick bites.

Arthritis is one of the most important symptoms of late-stage borreliosis, observed in approximately 60% of untreated patients with Lyme disease. In several percent of them, this manifestation is of interest to orthopedic surgeons. The authors present a case of a patient, working as a forester, who underwent left hip replacement arthroplasty having contracted a Borrelia burgdorferi infection in the past, and who was hospitalized 12 years before in the infectious ward due to suspected neuroborreliosis for which he was treated with Ceftriaxone 2 × 2.0 g intravenously for 4 weeks. At that time, a tomographic examination of the spinal cord revealed herniated nuclei at levels L4/L5 and L5/S1, which filled the left lateral recess, narrowing the intervertebral holes and compressing the nerve roots on the left side of L4 and L5. In September 2019, total hip replacement in the patient's left hip joint was performed. It is concluded that an active role of neuroborreliosis in this process of hip joint destruction may be suggested. Int J Occup Med Environ Health. 2021;34(5):693-9.

Evaluation of the results of posterior approach in thoracic disc herniation surgery.

The incidence of symptomatic intervertebral disc hernias in the thoracic segment is estimated at 1 case per million people per year, which is about 0.25-0.75% of all symptomatic intervertebral disc hernias and 0.15-1.85% of operative intervertebral disc diseases. AIM: The aim of the study was to assess the results of the surgical treatment of symptomatic discopathy in the thoracic spine through the posterior approach. MATERIALS AND METHODS: The results of the surgical treatment of 52 patients (35 women, 17 men) with symptomatic thoracic disc herniation in the Department of Neuroorthopedics in the years 2012-2019 were analyzed retrospectively. The neurological and functional status of patients before and after the surgery was assessed, as well as the average duration of the surgery and hospitalization, perioperative complications, intraoperative blood loss and the number of reoperations. Radiculopathy and myelopathy were the main indications for surgery. RESULTS: The largest group included patients operated on in the 5th and 6th decades of life, with women being the majority (67%). Hernia of the distal thoracic spine, i.e. Th10-Th11-Th12-L1, was most often operated on. According to the Frankel scale, the largest number of patients (47 before the surgery and 48 after the surgery) were qualified for groups D and E. As regards the WISCI scale the largest group of patients was classified as level 20. The rate of complications was 7%, the rate of neurological complications was 5.2% and the rate of reoperations was 3.5%. CONCLUSIONS: The vast majority of discopathies in the thoracic spine occur at lower levels, i.e. Th10-Th11-Th12-L1. The analysis of the functional status after the surgery of thoracic discopathy based on 2 scales showed a greater usefulness of the WISCI scale than the Frankel scale. A larger number of patients changed the group after surgery in the WISCI scale than in the Frankel scale. Therefore, we can conclude that the WISCI scale is more accurate in assessing the functional state of patients operated on due to thoracic discopathy.

Affinity of Antifungal Isoxazolo[3,4-b]pyridine-3(1H)-Ones to Phospholipids in Immobilized Artificial Membrane (IAM) Chromatography.

Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the approximation of the processes of absorption, distribution, metabolism, and elimination. Although the lipophilicity of drug candidates is determined using the shake flash method (n-octanol/water system) or reversed phase liquid chromatography (RP-LC), more biosimilar alternatives to classical lipophilicity measurement are currently available. One of the alternatives is immobilized artificial membrane (IAM) chromatography. The present study is a continuation of our research focused on physiochemical characterization of biologically active derivatives of isoxazolo[3,4-b]pyridine-3(1H)-ones. The main goal of this study was to assess the affinity of isoxazolones to phospholipids using IAM chromatography and compare it with the lipophilicity parameters established by reversed phase chromatography. Quantitative structure-retention relationship (QSRR) modeling of IAM retention using differential evolution coupled with partial least squares (DE-PLS) regression was performed. The results indicate that in the studied group of structurally related isoxazolone derivatives, discrepancies occur between the retention under IAM and RP-LC conditions. Although some correlation between these two chromatographic methods can be found, lipophilicity does not fully explain the affinities of the investigated molecules to phospholipids. QSRR analysis also shows common factors that contribute to retention under IAM and RP-LC conditions. In this context, the significant influences of WHIM and GETAWAY descriptors in all the obtained models should be highlighted.

Assessment of the results of occipito-cervical stabilization in cranio-vertebral damage.

Damage to the cranio-vertebral junction includes bone and ligament structures as well as the nervous system. Due to the unique structure of the occipital-atlanto-axial complex (C0-C1-C2) and biomechanical properties, they cause a surgical challenge. The aim of the surgery is to achieve bone fusion and stability of occipital-atlanto-axial complex. AIM: The aim of the study was to analyze the causes and effects of damage to the cranio-vertebral junction and the results of surgery with occipitocervical stabilization. MATERIALS AND METHODS: 43 patients who underwent occipital-cervical stabilization due to traumatic lesions in the C0-C1-C2 area were analyzed retrospectively in the 2000-2018 period in the Department of Neuroortopedia MCR STOCER. RESULTS: In 49%, the cause of trauma to the cranio-vertebral junction was a fall from a height, and it was in 37% a traffic accident. 70 % patients had C2 vertebra fracture with no stenosis of cervical canal and 14% had signs of C1-C2 instability. Politrauma was diagnosed in 9 patients and 23.3% of examined manifested neurological deficits. 70% of patients were in the 2nd group of risk according to the ASA scale. CONCLUSIONS: The analysis of damage to the cranio-vertebral junction showed that the main cause of injury was a fall. 21% patients presented tetraparesis. When qualifying patients after trauma to the craniovertebral junction for surgery, the degree of risk should be taken into account. Despite the high complication rate which was over 50 %, presented technique was effective because 95% patient achieved bone fusion and stability C0-C1-C2 complex.

Surgical treatment of thoracic disc herniation.

Symptomatic thoracic disc herniation is estimated on 1 person per million per year. 70% of all thoracic disc herniation cases are asymptomatic. This condition is often undiagnosed in regard to misguided clinical manifestations. Surgical treatment of symptomatic thoracic disc herniation is major challenge for spine surgeons because of the fact that thoracic spine has special anatomical conditions. Historically, posterior approach with laminectomy was treatment by choice, but this method was abandoned for some time, because of the high risk of postoperative complications. During last years we observe development of new approaches and advanced techniques e.g. microsurgical pedicle-sparing transfacet approach, costotransversectomy, extracavitary approach, minimal invasive thoracoscopic or endoscopic discectomy, but posterior approach is still broadly applied.

Lipophilicity Determination of Antifungal Isoxazolo[3,4-b]pyridin-3(1H)-ones and Their N1-Substituted Derivatives with Chromatographic and Computational Methods.

The lipophilicity of a molecule is a well-recognized as a crucial physicochemical factor that conditions the biological activity of a drug candidate. This study was aimed to evaluate the lipophilicity of isoxazolo[3,4-b]pyridine-3(1H)-ones and their N1-substituted derivatives, which demonstrated pronounced antifungal activities. Several methods, including reversed-phase thin layer chromatography (RP-TLC), reversed phase high-performance liquid chromatography (RP-HPLC), and micellar electrokinetic chromatography (MEKC), were employed. Furthermore, the calculated logP values were estimated using various freely and commercially available software packages and online platforms, as well as density functional theory computations (DFT). Similarities and dissimilarities between the determined lipophilicity indices were assessed using several chemometric approaches. Principal component analysis (PCA) indicated that other features beside lipophilicity affect antifungal activities of the investigated derivatives. Quantitative-structure-retention-relationship (QSRR) analysis by means of genetic algorithm-partial least squares (GA-PLS)-was implemented to rationalize the link between the physicochemical descriptors and lipophilicity. Among the studied compounds, structure 16 should be considered as the best starting structure for further studies, since it demonstrated the lowest lipophilic character within the series while retaining biological activity. Sum of ranking differences (SRD) analysis indicated that the chromatographic approach, regardless of the technique employed, should be considered as the best approach for lipophilicity assessment of isoxazolones.

Finegoldia magna the cause of hip revision surgery - a two case report.

The cause of septic arthritis in 20% of cases is anaerobic bacteria, including infections caused by Finegoldia magna. The occurrence of this pathogen in the etiology of postoperative post-implantive septic joint inflammations is estimated at 5-12% of all anaerobic infections, and 20-40% of all gram-positive anaerobic coccus (GPAC). CASE REPORTS: The 65-year-old male patient was admitted due to symptoms of pain in the left hip after having undergone arthroplasty three years prior. It was found that the relative length of the left lower limb was shortened by 1.5 cm and there was limited mobility of the left hip joint. The radiological image of the left hip indicated the loosening of the endoprosthesis, which qualified for a revision surgery. During hip revision surgery, the material was collected from the site, for microbiological examination, in which Finegoldia magna was detected, sensitive to Amoxicillin with Clavulanic acid, Clindamycin, Chloramphenicol, Imipenem, Metronidazole and Piperacillin with Tazobactam. Based upon the antibiogram, the patient was given piperacillin with tazobactam (Tazocin, Pfizer) 4 times a day 4.5 g intravenously over 7 days, resulting in a clinical improvement. The 55-year-old female patient was admitted due to recurrent exudates in left trochlear bursa which arose 5 years after left hip arthroplasty. The patient had limited movements in the left hip. Ulrasound diagnostics showed a presence of a thick fluid reservoir located under the fascia in the lateral side of the left thigh measuring 160 x 42 x 25 mm, which had contact with the hip joint. In the radiographic image of the joint, a cyst around the bottom of the implanted acetabular component was revealed. The patient underwent hip revision surgery, and an anaerobic bacterium Finegoldia magna was isolated from a swab taken from the acetabulum. The patient was given piperacillin with tazobactam (Tazocin, Pfizer) 4 times a day 4.5 g intravenously over 7 days, with good clinical effect. CONCLUSIONS: In both cases, the post-implantation septic infection was triggered by Finegoldia magna. Arthroplasty with subsequent antibiotic therapy resulted in an improvement of the patients' condition and joint reconstruction. In orthopedic practice it should be noted that infections due to the anaerobic bacteria Finegoldia magna may be the cause of complications after the arthroplasty of the joints.

Intradural disc herniation - report of two cases.

Intradural disc herniation is a very rare condition, which occurs in up to 0.3% cases of all disc herniations. It mostly develops at L4-L5 level, which is caused by the presence of strong adhesions between the posterior longitudinal ligament and dura mater. These rare cases are included in the classifications, however, they are associated with diagnostic difficulties, both in physical examination and in the image visible in magnetic resonance. REPORT OF 2 CASES: The presented patients were treated in the Neuroortopedic Department within the last two years. Despite previous examinations, the final diagnosis of intradural disc herniation occurred only during the surgery. CONCLUSIONS: Rarely occurring hernias of the intervertebral disc require increased vigilance among surgeon's spine physicians. Preoperative diagnosis of intradural lesion would make it possible to develop a better surgical strategy.

[Thrombosis of the medial artery imitating the symptoms of carpal tunnel syndrome - a case report]. / Zakrzepica tetnicy posrodkowej imitujaca objawy zespolu ciesni nadgarstka ­ opis przypadku.

Carpal tunnel cyndrome is a condition resulting from the compression of the median nerve in the wrist canal. Thrombosis of the medial artery can exceptionally rarely mimic the symptoms of carpal tunnel syndrome. A CASE REPORT: The 46-year-old woman reported with typical symptoms of carpal tunnel syndrome. The performed ultrasound examination did not confirm the suppression of the median nerve in the wrist canal. However, the median artery filled with a thrombus was described. After conservative treatment with heparin, the small-molecule discomfort in the patient subsided within 3 weeks. CONCLUSIONS: The rare causes of median nerve compression symptoms should be taken into account during ultrasound diagnostics of the carpal tunnel cyndrome using Doppler technique.

Static and Dynamic Loading Behavior of Ti6Al4V Honeycomb Structures Manufactured by Laser Engineered Net Shaping (LENSTM) Technology.

Laser Engineered Net Shaping (LENSTM) is currently a promising and developing technique. It allows for shortening the time between the design stage and the manufacturing process. LENS is an alternative to classic metal manufacturing methods, such as casting and plastic working. Moreover, it enables the production of finished spatial structures using different types of metallic powders as starting materials. Using this technology, thin-walled honeycomb structures with four different cell sizes were obtained. The technological parameters of the manufacturing process were selected experimentally, and the initial powder was a spherical Ti6Al4V powder with a particle size of 45-105 µm. The dimensions of the specimens were approximately 40 × 40 × 10 mm, and the wall thickness was approximately 0.7 mm. The geometrical quality and the surface roughness of the manufactured structures were investigated. Due to the high cooling rates occurring during the LENS process, the microstructure for this alloy consists only of the martensitic α' phase. In order to increase the mechanical parameters, it was necessary to apply post processing heat treatment leading to the creation of a two-phase α + ß structure. The main aim of this investigation was to study the energy absorption of additively manufactured regular cellular structures with a honeycomb topology under static and dynamic loading conditions.