ABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Acute Kidney Injury/chemically induced , Tumor Necrosis Factor-alpha/antagonists & inhibitors , Tomography, X-Ray Computed/methodsSubject(s)
Acute Kidney Injury/chemically induced , Antibodies, Monoclonal, Humanized/adverse effects , Antirheumatic Agents/adverse effects , Spondylitis, Ankylosing/drug therapy , Tuberculosis, Pulmonary/etiology , Tumor Necrosis Factor-alpha/antagonists & inhibitors , Adalimumab , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Antirheumatic Agents/therapeutic use , Antitubercular Agents/therapeutic use , Asymptomatic Diseases , Depression/complications , Depression/drug therapy , Diagnosis, Differential , Disease Susceptibility , Female , Humans , Incidental Findings , Middle Aged , Polypharmacy , Radiography , Sarcoidosis/diagnosis , Spinal Stenosis/complications , Spinal Stenosis/drug therapy , Spondylitis, Ankylosing/complications , Tuberculosis, Pulmonary/diagnostic imaging , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Urogenital/diagnosisABSTRACT
The authors present a case of acute and prompt symptomatic irritative urinary cystitis after transurethral resection (TR) of bladder cancer. The clinical presentation, like a irritative syndrome, was with a positive urine cultive to Enterococci and Staphylococcus. The physical examination, under general anesthesia (EBA), eliminated the urethral injury or the meatus trauma, so the urethral stenosis. The bladder view, in scaring processing yet, was congestive, bledding and edematous; an extensive white calcification was covering all the mucose surface bladder. The presumptive diagnosis was incrusted cystophatie (cystitis) and a transurethral resection (TR), along total bladder mucosa, was made so the result of pathological examination was sure. Intravenous and oral antimicrobial agent (Amoxicillin-Clavunan), in different ways, was instaured like a treatment, to achieve a negative urinary cultive, to eradicate the bacterial agents. We made a revision of the most important aspects in the clinical presentation, laboratory diagnosis and therapy, in this cystophatie that is not frequent, where the ureolitic bacterial agents have the responsibility, main Corynebacterium urealiticum, and where the recent urologic surgery or instrumentation, is narrowly related with the development of this cystophatie.
Subject(s)
Corynebacterium Infections/etiology , Cystectomy/adverse effects , Urinary Tract Infections/etiology , Urination Disorders/etiology , Acute Disease , Calcinosis/etiology , Humans , Male , Middle Aged , Syndrome , Time Factors , Urologic Diseases/etiologyABSTRACT
Presentamos un caso de sintomatología miccional aguda e inmediata después de RTU de neoplasia vesical. El cuadro miccional, de carácter irritativo, cursó con cultivo de orina positivo a Enterococo y Staphylococo. La exploración vesical bajo anestesia (EBA) descartó la afección uretral (estenosis). Todavía sin cicatrizar, se observó una mucosa vesical edematosa, congestiva y sangrante, cubierta por una extensa calcificación blanquecina. Con la impresión diagnóstica de cistopatía incrustante se realizó RTU de toda la mucosa vesical afecta (legrado). La anatomía patológica confirmó el diagnóstico. Se instauró tratamiento antibiótico (Amoxi-Clavulánico), en diferentes pautas, hasta que el cultivo de orina se negativizó. Se realiza revisión de los aspectos clínicos, diagnósticos y terapéuticos de esta cistopatía, no muy frecuente, donde las bacterias ureolíticas son los microorganismos responsables, fundamentalmente Corynebacterium ureolíticum, y donde la instrumentación endourológica está íntimamente relacionada con el desarrollo de la cistopatía (AU)
No disponible
Subject(s)
Middle Aged , Male , Humans , Urologic Diseases , Syndrome , Urination Disorders , Time Factors , Urinary Tract Infections , Cystectomy , Calcinosis , Corynebacterium Infections , Acute DiseaseABSTRACT
A series of 69 cases of systemic amyloidosis is discussed (12 primaries; 7 due to myeloma; 44 reactive; 5 due to familiar mediterranean fever and 1 portuguese familiar polyneuropathy) in which their clinical aspects, topographical distribution of the deposit and histochemical characteristics are studied using the potassium permanganate technique. According to sings and symptoms of presentation and topography there is a remarkable overlapping in the five types of amyloidosis. Only macroglossia was more frequent in primary amyloidosis (p less than 0.001). However the potassium permanganate technique can help in the classification. Considering the first clinical diagnosis. 83% of primary amyloidosis and 100% of amyloidosis due to myeloma, were resistant to permanganate. 84% of reactive amyloidosis and 100% of familiar mediterranean fever, were sensitive. The only case of portuguese familiar polyneuropathy showed resistance.
Subject(s)
Amyloidosis/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Amyloidosis/classification , Female , Histocytochemistry , Humans , Male , Middle Aged , Potassium PermanganateABSTRACT
Ten cases of acute febrile neutrophilic dermatosis or Sweet's disease have been studied clinically and histologically. Seventy percent of the patients were females with mean age of 43.1 +/-9 years. All of them presented the typical skin lesions consisting of papules and painful erythematous--edematous plaques in face, neck and upper chest. Fever was observed in seven patients and painful joints in four cases. One case presented polyarthritis of the big joints and there was one other case of conjuntivitis. The analytical data revealed a constant increase in sedimentation rate observed in 90% of patients. Leukocytosis was observed in 30% of patients and neutrophilia in 40%. Histologically, the lesions showed a neutrophilic infiltration of the skin without signs of vasculitis. Eight patients received treatment with Prednisone per os, one of whom, because of his relapses, was later given Potassium Iodine. Another patient was treated with Indomethacin, and one patient did not received any treatment. The evolution was favorable in all cases with sustained remissions. Sweet's Syndrome has been described associated mainly with acute myeloid leukemia in 10-20% of patients and in isolated instances with other systemic and neoplasic diseases. The concomitant conditions in 50% of our cases were: Ulcerative colitis, nodular sclerotic Hodgkin disease, infiltrative ductal carcinoma of the breast, carcinoma of the uterus neck and Crohn's disease; these last two associations had not been previously described in the literature.
Subject(s)
Fever , Skin Diseases/pathology , Adult , Female , Humans , Leukocytosis/pathology , Male , Middle Aged , Neutrophils , SyndromeABSTRACT
We report on a patient with verruciform xanthoma lesions in an epithelial nevus and developmental anomalies since birth that may be classified as CHILD syndrome (congenital hemidysplasia with ichthyosiform erythroderma and limb defects). Histological analyses of the lesion revealed verrucous features with acanthosis, hyperkeratosis, parakeratosis and the typical infiltrate of xanthomatous cells in dermal papillae. To our knowledge only 5 cases of verruciform xanthoma on epidermal nevus have been reported to date. In our view, the present case of CHILD syndrome is the first reported in which xanthomatous transformation has been revealed in biopsies taken when the girl was a baby.
Subject(s)
Abnormalities, Multiple/pathology , Xanthomatosis/pathology , Adolescent , Diagnosis, Differential , Female , Humans , Ichthyosis/pathology , Leg Length Inequality/pathology , Limb Deformities, Congenital , Nevus/pathology , Skin Neoplasms/pathology , SyndromeABSTRACT
Trichofolliculoma is a rare benign neoplasm originated from hair follicle. Although this tumor often shows a suggestive clinical appearance, an accurate diagnosis only can be established by histopathologic findings. We report a case of intranasal trichofolliculoma. To the best of our knowledge, trichofolliculoma has not been previously described in this location.
Subject(s)
Nose Neoplasms/pathology , Skin Neoplasms/pathology , Humans , Male , Middle Aged , Nasal CavityABSTRACT
We report a 39 year old female, who 6 years later of accidental injury with cactus bristles, developed granulomatous lesions in her face with an ulcerative tendency. Histopathologic picture showed granulomatous infiltrates filling the full-thickness of the dermis, with abundant number of multinuclead giant cells foreign-body-type and Langhans-type and mixed inflamatory infiltrate. In the dermo-hipodermal limit, several foreing bodies were found with a thorny or barb shape, some of them into the giant cells, with were PAS positive and showed a brilliant refractile aspect under polaroscopic examination.
Subject(s)
Facial Dermatoses/etiology , Granuloma, Foreign-Body/etiology , Plants , Adult , Facial Dermatoses/pathology , Female , Granuloma, Foreign-Body/pathology , HumansABSTRACT
We report a new case of localized Darier's disease or keratosis follicularis with successful response to topical retinoic acid treatment. We comment the clinical histopathological features and differential diagnosis of these uncommon variant which has only been reported in 10% of the patients.
Subject(s)
Darier Disease/drug therapy , Tretinoin/therapeutic use , Administration, Topical , Adult , Darier Disease/diagnosis , Darier Disease/pathology , Diagnosis, Differential , Female , Humans , Nevus/diagnosis , Skin Neoplasms/diagnosis , Tretinoin/administration & dosageSubject(s)
Hearing Disorders/diagnosis , Child , Child, Preschool , Deafness/diagnosis , Deafness/psychology , Hearing Disorders/psychology , Humans , Infant , Time FactorsABSTRACT
Acquired digital fibrokeratomas are uncommon benign fibrous tumors frequently situated on fingers. Histopathologic findings include an acanthotic hyperkeratotic epidermal envelope that surrounds a core of normal appearing connective tissue. Clinical, histopathological aspects and differential diagnosis are discussed.
