Salivary flow and xerostomia in older patients with type 2 diabetes mellitus.

OBJECTIVES: To assess salivary flow in older patients with type 2 diabetes mellitus (DM2) and its association with xerostomia. METHODS: Cross-sectional clinical study conducted with older patients diagnosed with type 2 diabetes for at least one year receiving treatment at the Integrated Center for Diabetes and Hypertension of Ceará (CIHD) in the city of Fortaleza, Ceará, Northeastern Brazil. Oral clinical examination was carried out to assess the decayed, missing and filled teeth index (DMFT). Perception of the presence of xerostomia/dry mouth was assessed using the Visual Analogue Scale. Stimulated salivary flow was measured and samples were obtained using an extra-soft silicone device. RESULTS: 120 older patients with diabetes (60 insulin-dependent and 60 non-insulin-dependent) aged 65-91 years, with a mean age of 72.26 ± 6.53 years, were assessed. Of these, 111 (92.5%) presented a decrease in salivary flow while 59 (49.2%) reported moderate to severe xerostomia/dry mouth. The DMFT Index presented a mean of 27.53 ± 4.86 teeth. CONCLUSIONS: Reduced salivary flow was found in the group assessed in the present research; however, this finding is not in accordance with the perception of xerostomia/dry mouth reported by the patients.

Princípios ativos de enxaguatórios bucais comercializados em fortaleza, seus tipos e suas informações / Active principles of oral mouthwashes commercialized in Fortaleza, their types and their information

Enxaguatórios bucais são substâncias antimicrobianas utilizadas como coadjuvante do controle mecânico do biofilme dentário na intenção de auxiliar na prevenção das doenças periodontais e cárie dentária. Entre os princípios ativos mais utilizados na composição dos enxaguatórios bucais encontram-se a clorexidina, cloreto de cetilpiridínio, triclosan, óleos essenciais e plantas medicinais. O objetivo deste estudo foi investigar os princípios ativos de enxaguatórios bucais comercializados em Fortaleza, comparando seus tipos e suas informações nos produtos e nos sites das principais empresas que os comercializam. Foram investigadas as composições químicas de enxaguatórios bucais nos sites dos principais fabricantes brasileiros de produtos de higiene oral (Colgate®; Oral-B®; Listerine®; Sanofi©; Sanifill®; Daudt®; Kleyhertz®; Bitufo®) na intenção de verificar os respectivos princípios ativos. Ao mesmo tempo, nas principais redes de farmácia da cidade de Fortaleza que atuam nacionalmente, a mesma investigação foi realizada diretamente no produto. Os enxaguatórios foram separados de acordo com o seu nome comercial, informações disponíveis no site, composição descrita no rótulo do produto e princípio ativo. Os resultados foram descritos de acordo com cada fabricante. Entre as 8 fábricas pesquisadas, 57 marcas comerciais de enxaguatórios bucais contendo os mais variados princípios ativos foram encontradas. O cloreto de cetilpiridínio foi o mais utilizado estando em produtos de 5 empresas. Pode-se concluir que os fabricantes nacionais de enxaguatórios bucais falham ao informar sobre os princípios ativos contidos em seus produtos, além de algumas empresas exagerarem na gama de produtos postos à venda, o que causa dificuldades ao dentista na hora de prescrever e ao paciente na hora de comprar (AU)

Mouthwashes are antimicrobial substances used as an adjunct to mechanical control of dental plaque in an attempt to help prevent periodontal disease and tooth decay. Among the most commonly used active ingredients in the composition of mouthwashes are chlorhexidine, cetylpyridinium chloride, triclosan, essential oils and medicinal plants. The aim of this study was to investigate the active ingredients of mouthwashes commercialized in Fortaleza, comparing their types and their information on the products and on the websites of major companies that sell them. Investigated the chemical compositions of mouthwashes on the websites of major Brazilian manufacturers of oral hygiene products (Colgate®; Oral-B®; Listerine®; Sanofi©; Sanifill®; Daudt®; Kleyhertz®; Bitufo®) in order to verify their active ingredients. At the same time, the leading drugstore chains in the city of Fortaleza that operate nationally, the same research was carried out directly on the product. The rinses were separated according to their trade name, information available on the website, composition described on the product labeland active ingredient. The results were described according to each manufacturer. Among the surveyed factories 8, 57 trademarks mouthwashes containing various active ingredients were found. The cetylpyridinium chloride is the most widely used being 5 in product companies. It can be concluded that the domestic manufacturers of mouthwashes fail to inform about the active ingredients contained in their products, and some companies exaggerate the range of products offered for sale, which causes difficulties to the dentist at the time of prescribing and patient in time to buy. (AU)