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1.
PLoS One ; 18(7): e0284706, 2023.
Article in English | MEDLINE | ID: mdl-37506098

ABSTRACT

INTRODUCTION: Chronic plantar ulcers in leprosy are lesions resulting from motor and sensory alterations caused by Mycobacterium leprae. They are lesions refractory to conventional dressings and present high recurrence rates. OBJECTIVE: To evaluate the epidemiological clinical profile of patients with chronic plantar ulcers associated with bony prominences in the lesion bed and to evaluate the efficacy of orthopedic surgical treatment of these lesions. METHODS: This is a descriptive and analytical retrospective study with the evaluation of medical records of patients undergoing surgical treatment of chronic plantar ulcers from 2008 to 2018. The surgical technique applied consisted of corrective resection of bone prominences and the primary closure of the lesion with bipediculated local flap. RESULTS: 234 patients were submitted to surgery, 55.1% male with an average age of 69.5 years old. Of these, 82.9% were illiterate; and 88.5% with open lesions over 10 years. After surgical treatment, total wound healing occurred in an average time of 12 weeks. The variables that contributed to shorter healing time were: Patients' lower age group; regular use of orthopedic shoes and insoles and dressings performed by nurse aides in health units before surgery. Obesity was the factor that correlated with the delay of healing time. CONCLUSION: A higher incidence was observed in males and male and female illiterate patients. The regular use of shoes and insoles and dressings performed by nurse aides in health units contributed to shorter postoperative healing time. Orthopedic surgical treatment with corrective resection of bony prominences proved to be an efficient therapeutic method for the closure of chronic plantar ulcers. It is a reproducible method, justifying the importance of the orthopedic surgeon in the context of the multidisciplinary team to cope with these complex lesions.


Subject(s)
Diabetic Foot , Foot Ulcer , Leprosy , Orthopedic Procedures , Humans , Male , Female , Aged , Foot Ulcer/epidemiology , Foot Ulcer/etiology , Foot Ulcer/surgery , Retrospective Studies , Leprosy/complications , Leprosy/epidemiology , Leprosy/surgery , Orthopedic Procedures/adverse effects , Surgical Flaps/surgery , Diabetic Foot/surgery
2.
Toxicon ; 119: 266-9, 2016 Sep 01.
Article in English | MEDLINE | ID: mdl-27368713

ABSTRACT

Scorpion stings are a public health problem in the Brazilian Amazon. However, detailed clinical characterization with the proper animal identification is scarce. Here we report a confirmed case of envenoming by Tityus cf. silvestris in the Brazilian Amazon. The case evolved with generalized muscle spasms and was treated with antivenom and supportive therapy, requiring intensive care unit admission. The patient evolved favourably and was discharged after 9 days of hospitalization.


Subject(s)
Antivenins/therapeutic use , Scorpion Stings/drug therapy , Spasm/chemically induced , Adult , Animals , Brazil , Humans , Male , Scorpions , Treatment Outcome
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