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Bioorg Med Chem Lett
; 14(5): 1119-21, 2004 Mar 08.
Article
in English
| MEDLINE
| ID: mdl-14980648
ABSTRACT
A series of derivatives of 2,4- and 2,5-thiazolyl- or oxazolylbenzenesulphonamides has been prepared and evaluated as potential MMP inhibitors. The thiazole 15b have been found to exhibit MMP-2 and MMP-9 inhibitions higher than reference compounds GI 129471 and CGS 27023A.