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3.
Gig Sanit ; (5): 22-5, 1997.
Article in Russian | MEDLINE | ID: mdl-9378339

ABSTRACT

Qualitative and quantitative analyses of the environment and human health during 5 years before and after the Chernobyl accident (1986) provided an original scheme and methods for hygienic assessment of the negative influence of environmental pollution on health. They were tested in the Kiev Region. The accident was found to essentially complicated the environmental and sanitary situation in the region and to negatively affect human health.


Subject(s)
Environmental Pollution , Health Status , Power Plants , Radioactive Hazard Release , Adult , Air Pollution, Radioactive , Cesium Radioisotopes/analysis , Child , Environmental Pollutants/analysis , Food Contamination, Radioactive/analysis , Humans , Infant, Newborn , Strontium Radioisotopes/analysis , Time Factors , Ukraine , Water Pollution, Radioactive
4.
Ukr Biokhim Zh (1978) ; 65(1): 107-10, 1993.
Article in Russian | MEDLINE | ID: mdl-8351734

ABSTRACT

An increase in frequency of heart contractions, changes in the bioelectrical heart activity and decrease of the force-pump heart function are observed in the rabbits with model chronic ischemic heart disease lipid metabolism in significantly changed the concentration of cholesterol in the right ventricle myocardium as well as the concentrations of unsaturated lipid acids in the heart tissues increase, while the content of saturated lipid acids and antioxidant activity of plasma decrease. Bioenergetic processes change as follows: succinate-dehydrogenase and alpha-keto-glutarate-dehydrogenase activity decrease, while the concentrations of glycogen, lactic and pyruvic acids and lactate dehydrogenase activity in the heart tissues increase.


Subject(s)
Cholesterol, Dietary/administration & dosage , Myocardial Ischemia/metabolism , Animals , Cholesterol/metabolism , Chronic Disease , Disease Models, Animal , Glycogen/metabolism , Ketoglutarate Dehydrogenase Complex/metabolism , L-Lactate Dehydrogenase/metabolism , Lactates/metabolism , Lactic Acid , Lipid Metabolism , Myocardial Contraction/physiology , Myocardial Ischemia/chemically induced , Oxidation-Reduction , Pyruvates/metabolism , Pyruvic Acid , Rabbits , Succinate Dehydrogenase/metabolism
5.
Ukr Biokhim Zh (1978) ; 64(6): 101-4, 1992.
Article in Russian | MEDLINE | ID: mdl-1488803

ABSTRACT

While laboratory experimental model of coronary heart disease (according to Frol'kis et al.) is developed, activity of succinate dehydrogenase, alpha-ketoglutarate dehydrogenase, Na+, Ka(+)- and Mg2+ ATPase decreases, but activity of lactate dehydrogenase and concentrations of lactic and pyruvic acids in the heart tissue increase. At the same time concentration of glycogene increases more than twice. As far as we can see there is an evidence of a decrease of glycogene utilization due to change in levels of regulatory processes. Despite a decrease of ATP synthesis by the inhibition of tricarboxylic acid cycle the ATP:ADP relation reduces to ATP, as emphatic inhibition of ATPase in the heart tissues takes place in development of the model of the coronary heart disease. The relation between ATP and ADP is considered as a regulator of glycogene utilization. In the liver tissue activity of succinate dehydrogenase, alpha-ketoglutarate dehydrogenase, Na+, K(+)- and Mg2+ ATPase falls, while concentrations of lactic acid grow. No accumulation of glycogen is observed. It is obvious that there are controversial metabolic processes. Experimental data are discussed.


Subject(s)
Glycogen/metabolism , Liver Glycogen/metabolism , Liver/metabolism , Myocardial Ischemia/metabolism , Myocardium/metabolism , Animals , Chronic Disease , Disease Models, Animal , Energy Metabolism , Glycogen/analysis , Liver/chemistry , Liver Glycogen/analysis , Myocardium/chemistry , Oxidation-Reduction , Rabbits
9.
Vrach Delo ; (5): 84-6, 1991 May.
Article in Russian | MEDLINE | ID: mdl-1866928

ABSTRACT

It is concluded that polyvinyl plastisols of the mentioned brands should not be used for manufacturing medical products. Only the P brand may be employed for manufacturing balloons for measurement of the blood pressure and for inhalers.


Subject(s)
Equipment and Supplies , Polyvinyl Chloride/toxicity , Animals , Maximum Allowable Concentration , Polyvinyl Chloride/chemistry , Rats
10.
Kosm Biol Aviakosm Med ; 25(3): 50-2, 1991.
Article in Russian | MEDLINE | ID: mdl-1685209

ABSTRACT

The irritating, sensitizing, and toxic effect of water produced by the method of carbon dioxide hydration was examined in animal experiments and human observations. It was found that before and after decontamination this water did not cause skin irritation or organism sensitization, did not have a toxic effect on the CNS, liver, kidneys or blood morphology, and did not deteriorate adaptive capabilities of the animal or human body.


Subject(s)
Aerospace Medicine , Carbon Dioxide/chemical synthesis , Ecological Systems, Closed , Hydrogen Bonding , Nickel/toxicity , Space Flight , Water Pollutants, Chemical/toxicity , Water Supply/standards , Animals , Guinea Pigs , Humans , Nickel/isolation & purification , Rats , USSR , Water Pollutants, Chemical/isolation & purification , Water Supply/analysis
11.
Vrach Delo ; (1): 97-9, 1991 Jan.
Article in Russian | MEDLINE | ID: mdl-2011911

ABSTRACT

A 10-day course of ultraviolet radiation (intensity: 1/8-2 biodoses daily) did not favour accumulation of cesium-137 in the body but produced some effect on the accumulation of strontium-90. In the real radiation condition in the city of Kiev the daily prophylactic 1/8 biodose may be considered as absolutely safe.


Subject(s)
Cesium Radioisotopes/pharmacokinetics , Strontium Radioisotopes/pharmacokinetics , Ultraviolet Rays , Animals , Dose-Response Relationship, Radiation , Male , Rats , Time Factors
14.
Vrach Delo ; (11): 102-4, 1990 Nov.
Article in Russian | MEDLINE | ID: mdl-2098962

ABSTRACT

Conditions are described of gaseous-chromatic analysis of inorganic mixtures contained in medical oxygen using chromatography with a detector of thermal conductivity. The relative error of determination does not exceed +/- 10%.


Subject(s)
Oxygen/isolation & purification , Chromatography, Gas/instrumentation , Chromatography, Gas/methods , Oxygen/analysis
17.
Gig Sanit ; (5): 74-6, 1990 May.
Article in Russian | MEDLINE | ID: mdl-2204591

ABSTRACT

Data presented by the authors testifies to the fact that neither 2 weeks, nor one month after the 10-day course of ultraviolet irradiation (UVR) with an intensity from 1/4 up to 2 biodoses daily changes in calcium, sodium and potassium content in blood serum of laboratory animals (white rats) were detected. At the same time, 2 weeks following the cessation of UVR course a tendency towards calcium accumulation in the whole organism of laboratory animals was observed, which was most noticeable+ after daily 10-day exposure to UVR with an intensity from 1/2 up to 1 biodose. The tendency was still present one month following the termination of UVR course. The total sodium and potassium store in the whole organism of laboratory animals did not practically change either immediately, or 2 weeks, or 1 month after the termination of 10-day UVR course with the intensity from 1/4 to 2 biodoses daily.


Subject(s)
Calcium/radiation effects , Potassium/radiation effects , Sodium/radiation effects , Ultraviolet Rays , Whole-Body Irradiation , Animals , Calcium/metabolism , Dose-Response Relationship, Radiation , Male , Potassium/metabolism , Radiation Dosage , Rats , Sodium/metabolism , Time Factors
19.
Vrach Delo ; (1): 106-9, 1990 Jan.
Article in Russian | MEDLINE | ID: mdl-2330692

ABSTRACT

The authors evaluated the problems of hygienic aspects of oxygen obtained by the method of electrolytic decomposition of water with a different content of chemical substances in the system with a hard polymere electrolyte. On the basis of sanitary-chemical qualities and toxicological properties electrolysis gaseous oxygen may be recommended for use in creating an artificial gaseous atmosphere in hermetically sealed compartments in mixture with gaseous nitrogen (ratio 1:4).


Subject(s)
Electrolysis , Oxygen/toxicity , Polymers/toxicity , Animals , Environment, Controlled , Male , Nitrogen/toxicity , Oxygen/isolation & purification , Rats , Time Factors
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