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Science ; 332(6034): 1149; author reply 1149, 2011 Jun 03.
Article in English | MEDLINE | ID: mdl-21622707

ABSTRACT

Wolfe-Simon et al. (Research Articles, 3 June 2011, p. 1163; published online 2 December 2010) argued that the bacterial strain GFAJ-1 can vary the elemental composition of its biomolecules by substituting arsenic for phosphorus. Although their data show that GFAJ-1 is an extraordinary extremophile, consideration of arsenate redox chemistry undermines the suggestion that arsenate can replace the physiologic functions of phosphate.


Subject(s)
Arsenic/metabolism , Halomonadaceae/metabolism , Phosphorus/metabolism , Adaptation, Physiological , Arsenates/chemistry , Arsenic/analysis , Arsenic/chemistry , Arsenites/chemistry , Halomonadaceae/growth & development , Molecular Structure , Oxidation-Reduction , Phosphates/chemistry
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