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Dent Clin North Am ; 56(2): 373-86, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22480809

ABSTRACT

Normal-sleeping individuals experience a lower metabolic rate and relative cardiovascular quiescent state with lower heart rate and blood pressure that naturally occurs during sleep compared with the waking state. In patients with obstructive sleep apnea (OSA), this quiescent state becomes disrupted. Research has shown a higher risk for several medical disorders, most ominous being a myocardial infarction or stroke. This article serves as an overview to the cardiovascular, cerebrovascular, metabolic, and gastroesophageal effects of OSA.


Subject(s)
Cardiovascular Diseases/etiology , Diabetes Mellitus, Type 2/etiology , Metabolic Syndrome/etiology , Sleep Apnea, Obstructive/complications , Gastroesophageal Reflux/etiology , Humans , Hypertension/etiology , Insulin Resistance/physiology , Oxidative Stress/physiology , Sleep Apnea, Obstructive/physiopathology , Stroke/etiology
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