[Normobaric pulsed hypoxic stimulation in the combined therapy of periodontitis in adolescents]. / Impul'snaia normobaricheskaia gipoksicheskaia stimuliatsiia v kompleksnoi terapii parodontita u podrostkov.

Hypoxic stimulation was added to local therapy of periodontitis in 26 adolescents with the initial manifestations of this condition. Analysis of the results has shown that hypoxic stimulation enhanced the body adaptive and compensatory potentialities, was conductive to recovery of the disordered oxygen metabolism and normalization of the regional hemodynamics and periodontal microcirculation.

[Changes in the blood microcirculation in the mouth mucosa in experimental stomatitis]. / Izmeneniia gemomikrotsirkuliatsii v slizistoi obolochke polosti rta pri éksperimental'nom stomatite.

Aphthous lesions in the oral mucosa (OM) were simulated in dog experiments by ligation of the common bile duct. In one of the experimental groups the beta-adrenoblocker propranolol was administered 30 min before surgery. Two hours after surgery the animals manifested changes in blood microcirculation of the OM. In animals treated with propranolol, the characteristics of blood microcirculation remained within normal. It is concluded that the development of aphthous lesions is preceded by functional disorders of blood microcirculation in the OM which are probably related to alterations in the neurovascular system.

[Vasoactive hormones and mediators in the mechanism of the development of an aphthous process in the oral mucosa]. / Vazoaktivnye gormony i mediatory v mekhanizmakh razvitiia aftoznogo protsessa na slizistoi obolochke polosti rta.

Experiments on dogs were made to simulate aphthous process on the oral mucosa by occlusion of the common bile duct. The content of adrenaline, noradrenaline, serotonin, histamine and ascorbic acid was measured during the development of pathological process in the areas of oral mucosa tissue characterized by most frequent appearance of aphthas and in the tissue of the duodenal, small and large intestine mucosa. The magnitude of the characteristics indicated was determined 2, 6 and 12 h and 1, 3, 7 and 10 days after operation. Aphthas appeared on the 3d day. Within the first hours of the experiment there was a considerable increase in the content of noradrenaline, adrenaline and serotonin in the oral mucosa accompanied by a reduction in the histamine and ascorbic acid content. In the intestinal mucosa, shifts in the correlations between the hormones and transmitters were less pronounced. During aphthas appearance, the histamine content rose whereas other parameters decreased. The period of the reverse development was characterized by the recovery of the correlations of the hormones under study and transmitters.

[Effect of laser radiation on the process of tissue vascularization after damage]. / Vliianie lazernogo oblucheniia na protsess vaskuliarizatsii tkani posle ee povrezhdeniia.

The pattern of influence of helium-neon laser irradiation on the process of revascularization, one of the most important stages of wound healing, is described. By the 16th day of the experiment, microvessels in the experimental animals were found to occupy than half of the area of the "regeneration table" of a transparent chamber implanted into the rabbit ear, while in the control animals only one-fourth of the area was occupied. Complete revascularization of the regenerating tissue in irradiated animals was completed by 20-22 days of the experiment and in controls only by 25-27 days. The results indicate the stimulating effect of laser rays on the process of restoration of hemomicrocirculation in damaged tissues.

[Reaction of vessels of the microcirculatory bed of subcutaneous tissue to exposure to an argon laser beam]. / Reaktsiia sosudov mikrotsirkuliatornogo rusla podkozhnoi kletchatki na vozdeistvie lucha argonovogo lazera.

The effect of argon laser irradiation on the microvessels of the subcutaneous fat tissue of rabbit's ear placed into Clark's transparent chamber was studied. Capillaries and venules were found to be sensitive to argon laser irradiation; functional disturbances of microcirculation were most distinct. Following laser irradiation an active reconstruction of the microcirculatory bed with the redistribution of the blood stream took place along with destruction of the vascular wall and perivascular inflammation.