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BMJ Case Rep ; 20162016 Jan 05.
Article in English | MEDLINE | ID: mdl-26733433

ABSTRACT

Polyarteritis nodosa (PAN) is a rare, severe form of vasculitis affecting medium-sized vessels. It manifests as a multisystem syndrome, and may be associated with hepatitis B virus-associated PAN (HBV-PAN) although the incidence of this is declining with better vaccination strategies and awareness of bloodborne virus screening. We report a case in which a patient displayed many classical features of the disease, occurring separately over a period of months and leading to contact with various medical specialties. Managing each symptom in isolation led to a number of misdiagnoses (including testicular cancer) and the patient experienced considerable psychological stress and morbidity as a result. The case was complicated by acute pancreatitis developing after an initial treatment response. This may have been iatrogenic (as a consequence of either entecavir or steroids) or secondary to PAN. For our patient, this led to a protracted clinical course but eventual complete resolution of both pathologies.


Subject(s)
Delayed Diagnosis , Hepatitis B/complications , Polyarteritis Nodosa/diagnosis , Angiography , Diagnosis, Differential , Hepatitis B virus/isolation & purification , Humans , Male , Middle Aged , Pain/etiology , Pancreatitis/etiology , Polyarteritis Nodosa/virology , Testicular Neoplasms/diagnosis
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