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Antimicrob Agents Chemother ; 6(5): 651-2, 1974 Nov.
Article in English | MEDLINE | ID: mdl-15825322

ABSTRACT

A quantitative microbiological assay and a bioautography system with Penicillium avellaneum UC-4376 was developed for the antitumor drugs maytansine, and its homologues, maytanprine and maytanbutine. The susceptibility of the assay is 1.5 mug/ml.


Subject(s)
Antineoplastic Agents, Phytogenic/analysis , Maytansine/analysis , Chromatography , Dose-Response Relationship, Drug , Maytansine/pharmacology , Penicillium/drug effects
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