ABSTRACT
The effects of exogenous ethanol and/or folic acid on endogenous homocysteine (HoCys) and SAM (S-adenosylmethionine)/SAH (S-adenosylhomocysteine) levels in chick brains were studied at 11 days of development. Embryonic EtOH (3.0 mmol/kg egg) exposure caused a 1.6-fold increase in brain HoCys levels and a 9-fold decrease in brain SAM/SAH levels as compared to controls (pSubject(s)
Brain/drug effects
, Chick Embryo/drug effects
, Ethanol/toxicity
, Folic Acid/therapeutic use
, Hyperhomocysteinemia/chemically induced
, Hyperhomocysteinemia/prevention & control
, Taurine/metabolism
, Animals
, Brain/metabolism
, Chick Embryo/embryology
, Chick Embryo/metabolism
, Folic Acid/pharmacology
, Hyperhomocysteinemia/metabolism
