Epidemiology of rosacea in Colombia.

BACKGROUND: Prevalence of rosacea has been estimated around the world in the range of 0-22%. In Colombia, the prevalence of rosacea remains unknown. The aim of this study was to determine the prevalence of rosacea and the frequencies of its subtypes in Colombia. METHODS: This cross-sectional, multicenter study was conducted in six outpatient dermatology clinics across Colombia. A total of 33 dermatologists conducted a comprehensive medical history and physical examination for all rosacea patients seen at their offices over the course of 2 months. All patients who accepted to participate were encouraged to answer a survey about the history of their illness. RESULTS: Of 10,204 outpatients evaluated for rosacea between July and August 2014, 291 rosacea patients were included in this study. The prevalence of rosacea subtypes in this cohort was: 45.3% erythematotelangiectatic (ETR) (n = 132), 48.7% papulopustular (PPR) (n = 142), 4.8% phymatous (n = 14), and 1% ocular (n = 3). CONCLUSIONS: Overall, the prevalence in Colombia was 2.85%. Our data represent an important first step to understanding the current state of rosacea in Colombia. The prevalence of rosacea in Colombia is the highest in Latin America among a few reports published, which might be explained by geographic features. However, contrary to our expectations, the prevalence is lower than that in some European countries. We postulate that this finding may be due to methodological differences.

Update on skin repigmentation therapies in vitiligo.

Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable knowledge accumulated during several decades on the pathogenic mechanisms, revealed important clues for designing new strategies to improve vitiligo depigmentation. With available medical therapies, high repigmentation percentages mostly on facial and neck lesions are achieved, although they are less effective on trunk and limbs and poor on the acral parts of the extremities. Narrow band UVB and psoralens and UVA are the two most important treatments for generalized vitiligo affecting more than 10-20% of the cutaneous surface, and topical corticosteroids, or calcineurin inhibitors are the most valuable treatments for localized vitiligo. Persistence of achieved regimentation is variable and an undefined percentage of patients may have variable recurrence. When vitiligo becomes refractory, surgical methods may improve depigmentation as effectively as with medical therapy; in segmental (unilateral) or long standing, non-segmental (bilateral) stable vitiligo, repigmentation with surgical methods is usually permanent.

Menopausia y piel III / Menopause and III skin

La piel constituye la barrera que defiende al resto del cuerpo de las influencias externas y simultáneamente, hace posible que se adapte a diferentes ambientes. Por tanto, su propia salud depende de una gran variedad de factores, tales como el recambio celular continuo, la calidad y funcionamiento de capilares sanguíneos, entre otros, que deben mantenerse en un balance perfecto para mantenerse sana. Los estrógenos y otras hormonas sexuales esteroideas, tienen gran influencia en este equilibrio. Los cambios que suceden durante la menopausia, como el hipoestrogenismo, se suman a los que conlleva el fotoenvejecimiento y el envejecimiento cronológico, ocasionando profundas alteraciones en la piel. La terapia Hormonal de Reemplazo (THR), por tanto, es de gran importancia