1.
In Vitro
; 13(6): 378-88, 1977 Jun.
Article
in English
| MEDLINE
| ID: mdl-69606
Subject(s)
Dihydrotestosterone/metabolism , Epithelial Cells , Epithelium/metabolism , HeLa Cells/metabolism , Testosterone/metabolism , Androstane-3,17-diol/biosynthesis , Androstanes/metabolism , Androstenediols/metabolism , Androstenedione/biosynthesis , Androsterone/biosynthesis , Carbon Radioisotopes , Cell Line , Fibroblasts/metabolism , Humans , Male , Prostatic Hyperplasia , Skin , Tritium
2.
Proc Natl Acad Sci U S A
; 70(5): 1419-22, 1973 May.
Article
in English
| MEDLINE
| ID: mdl-4514312
ABSTRACT
Three clones of ectopic hormone-producing cells from a single human neoplasm (bronchogenic carcinoma) show different rates of synthesis and secretion of chorionic gonadotropin and its alpha and beta subunits. For each clone, the amount of one or the other subunit always exceeded that of the complete hormone molecule. These findings may be analogous to unbalanced immunoglobulin chain synthesis in certain forms of myeloma.
Subject(s)
Carcinoma, Bronchogenic/metabolism , Chorionic Gonadotropin/metabolism , Hormones, Ectopic/metabolism , Lung Neoplasms/metabolism , Cells, Cultured , Chorionic Gonadotropin/analysis , Chorionic Gonadotropin/biosynthesis , Clone Cells , Hormones, Ectopic/analysis , Hormones, Ectopic/biosynthesis , Humans , Karyotyping , Male , Middle Aged , Radioimmunoassay
3.
Biochem Biophys Res Commun
; 43(3): 516-23, 1971 May 07.
Article
in English
| MEDLINE
| ID: mdl-4327442
