ABSTRACT
INTRODUCTION: Mesalazine or 5 aminosalicylic acid (5 ASA) is currently a first choice drug in the treatment of inflammatory bowel disease. It has been shown that it crosses the placenta and is excreted into breast milk in small quantities. CASE REPORT: We present the case of a four month old breast fed infant, with a thrombosis of the superior sagittal sinus secondary to a severe thrombocytosis (1,124,000/mm3). The only interesting antecedent we would draw attention to, is that breast feeding had been suddenly stopped the week before. The mother, suffering Crohn s disease, had been receiving treatment with oral mesalazine throughout her pregnancy and during lactation. CONCLUSIONS: Once other causes of the thrombocytosis had been eliminated, we based our approach on the hypothesis that it was due to prolonged intake of 5 ASA by the mother.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Cranial Sinuses/pathology , Mesalamine/adverse effects , Thrombosis/chemically induced , Thrombosis/diagnosis , Breast Feeding , Child , Cranial Sinuses/diagnostic imaging , Female , Humans , Infant , Maternal Exposure , Maternal-Fetal Exchange , Pregnancy , Radiography , Thrombocytosis , Thrombosis/pathologyABSTRACT
Se revisa la situación de la lactancia materna en nuestra comunidad en el intervalo comprendido entre 1986 y 1993. Para ello se estudian dos grupos de neonatos navarros totalmente comparables entre sí, que proceden de nuestra principal maternidad. Se comparan las cifras de prevalencia de los diversos tipos de lactancia en el momento del alta de maternidad y de modo mensual hasta el sexto mes de vida. Del presente trabajo pueden extraerse las siguientes conclusiones: 1. La categoría de lactancia materna vigente en Navarra es el tipo I de la OMS.2. La lactancia materna se sigue abandonando de modo precoz y masivo a lo largo del primer semestre de vida en Navarra siendo sus cifras indetectables al sexto mes.3. Apenas existen diferencias significativas entre las cifras del año 1986 y 1993 (AU)
Subject(s)
Pregnancy , Female , Infant , Humans , Infant, Newborn , Breast Feeding/statistics & numerical data , Hospitals, Maternity/statistics & numerical data , Spain/epidemiology , Prevalence , Mother-Child Relations , Infant CareABSTRACT
The state of breast-feeding in our autonomous community between 1986 and 1993 is reviewed. Two comparable Navarrese neonatal groups from our main maternity hospital are studied. The prevalence of the different types of breast-feeding at the time of discharge from the maternity hospital is compared, as well as monthly rates until the sixth month of life. The following conclusions can be drawn from this study: 1. The category of breast-feeding in Navarra is type 1 of the WHO. 2. Breast-feeding is abandoned in an early and massive way throughout the first six months of life in Navarra, with figures for this practice being undetectable by the sixth month. 3. There are barely any significant differences between the figures for 1986 and 1993.
