Integrated monitoring for environmental health impact assessment related to the genotoxic effects of vehicular pollution in Uberlândia, Brazil.

The development of parameters to explore the link between air-related diseases and their significant driving forces is an important aim in terms of national economics and public health. In this study, we did an integrated analysis involving multiple environmental health indicators from Uberlândia, Brazil, registered before and during a period when the Brazilian government reduced taxes on new cars in a bid to bolster local manufacturing. In addition, the present study utilized Driving Force-Pressure-State-Exposure-Effect-Action (DPSEEA) frameworks to evaluate correlations in environmental health indicators over 10 years (2004-2013), in which the Brazilian government reduced vehicle production taxes beginning in 2008. Significant correlations in all indicators selected were found from 2008 to 2013, corresponding to the tax reduction on new vehicles. The frequency of micronuclei (MN) was significantly higher in the city center compared to the reference site, with the highest MN levels observed during the period of reduced taxes. Results reinforced the need to adopt air quality monitoring programs in major cities.

Biomonitoring air quality during and after a public transportation strike in the center of Uberlândia, Minas Gerais, Brazil by Tradescantia micronucleus bioassay.

The aim of this study was to address the lack of information concerning the air quality in the city of Uberlândia, Minas Gerais, Brazil. In this study, we conducted an unprecedented experiment involving the in situ biomonitoring of air genotoxicity in the city center during and after a public transportation strike using the Tradescantia micronucleus test. The frequency of micronuclei was significantly higher in the city center compared with the reference site (Mann-Whitney test, p < 0.05), with the highest MN levels being observed during public transport stoppage (Kruskal-Wallis, Dunn p < 0.01). In addition, the multiple linear regression analyses revealed that the low circulation of buses during public transport stoppage and the increase in the concentration of particulate matter from the increased flow of vehicles in the city center during the strike positively influenced the MN frequency. The climatic factors did not change during the biomonitoring period, reflecting the fact that climatic factors did not influence the MN frequency.